Fine Structure of the Pancreatic Islets in Domestic Fowl with Special Reference to the Cell Type and Secretion

Watanabe, Takatomo; Paik, Young Ki; Yasuda, Mikio

doi:10.1679/aohc1950.38.259

Cited by 18 publications

(12 citation statements)

References 33 publications

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“…Because they were mainly located in close proximity to the Golgi apparatus during all of the developmental stages, it can be assumed that they are immature A granules. This type of A granules present in the embryonic grass snake pancreas were similar to those that have been described in the pancreas of adult vertebrates such as the marine teleost Fugu rubripes rubripes (Kobayashi et al, ), Japanese silver crucian carp Carassius langsdorfii (Kobayashi & Takahashi, ), toad Bufo vulgaris formosus (Kobayashi, ), domestic fowl Gallus gallus domesticus (Machino et al, ; Watanabe, Paik, & Yasuda, ), rat (Rall, Pictet, Williams, & Rutter, ), guinea pig (Bencosme & Pease, ; Caramia et al, ), and cat (Bencosme & Pease, ). Similar features of A granules were also described in the pancreas of rat, mouse, and chick embryos (Pictet & Rutter, ).…”

Section: Discussionsupporting

confidence: 78%

Ultrastructure of endocrine pancreatic granules during pancreatic differentiation in the grass snake, Natrix natrix L. (Lepidosauria, Serpentes)

Kowalska

Rupik

2017

Journal of Morphology

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We used transmission electron microscopy to study the pancreatic main endocrine cell types in the embryos of the grass snake Natrix natrix L. with focus on the morphology of their secretory granules. The embryonic endocrine part of the pancreas in the grass snake contains four main types of cells (A, B, D, and PP), which is similar to other vertebrates. The B granules contained a moderately electron-dense crystalline-like core that was polygonal in shape and an electron-dense outer zone. The A granules had a spherical electron-dense eccentrically located core and a moderately electron-dense outer zone. The D granules were filled with a moderately electron-dense non-homogeneous content. The PP granules had a spherical electron-dense core with an electron translucent outer zone. Within the main types of granules (A, B, D, PP), different morphological subtypes were recognized that indicated their maturity, which may be related to the different content of these granules during the process of maturation. The sequence of pancreatic endocrine cell differentiation in grass snake embryos differs from that in many vertebrates. In the grass snake embryos, the B and D cells differentiated earlier than A and PP cells. The different sequence of endocrine cell differentiation in snakes and other vertebrates has been related to phylogenetic position and nutrition during early developmental stages.

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Section: Discussionsupporting

confidence: 78%

Ultrastructure of endocrine pancreatic granules during pancreatic differentiation in the grass snake, Natrix natrix L. (Lepidosauria, Serpentes)

Kowalska

Rupik

2017

Journal of Morphology

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“…These data suggest that GLP-1 function might be mediated by somatostatin secreted from pancreatic D cells via GLP-1R in the avian species. Fehmann and Habener (1991) and Japanese quails (Smith, 1974;Watanabe et al, 1975;Schwarz et al, 1983;Mikami et al, 1985;Lucini et al, 1996). Weir et al (1976) have shown that somatostatin immunoreactivity in the chicken pancreas was 21 times higher than that in the rat.…”

Section: White Leghorn Chicken (G Gallus Domesticus) Is a Domesticatmentioning

confidence: 99%

Glucagon-like Peptide-1 Receptor Expression in the Pancreatic D Cells of Three Avian Species; White Leghorn Chickens, Northern Bobwhites, and Common Ostriches

et al. 2018

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Glucagon-like peptide (GLP)-1 is released from the intestinal L cells in response tofood ingestion and stimulates insulin secretion from the pancreatic B cells, by binding to its specific receptor (GLP-1R), which is expressed on the pancreatic B cells in the mammalian pancreas. Previously, we demonstrated that chicken GLP-1R was expressed on the pancreatic D cells by using a specific antibody against chicken GLP-1R. In the present study, we compared the localization of GLP-1R in the pancreases of three avian species; white leghorn chicken, northern bobwhite, and common ostrich, using the double immunofluorescence technique. We found that the types of pancreatic islets in the northern bobwhite pancreas were similar to those found

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“…The direct and specific action of alloxan on the B cells has singled out Bcell as the focus of alloxanized pancreas [1]. In spite of the numerous cytological studies on the avian pancreatic islets [3,5,8,9], morphological interrelationship between the exocrine and endocrine pancreatic has not yet been cleared. Our preliminary study in avian pancreas, however, revealed that the intercalated ducts which are part of exocrine pancreatic duct have been observed in the pancreatic islets of the avian [4].…”

Section: Resultsmentioning

confidence: 99%

Intercalated Duct Cells in the Chicken Pancreatic Islet with Special Reference to the Alloxan Administration.

Mutoh

Wakuri

Taniguchi

1999

The Journal of Veterinary Medical Science

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ABSTRACT. The intercalated duct cells were observed in the A and B islets of the chicken pancreas. These cells adhered with each other by intercellular junctional complexes at the apical side. They had many microvilli projecting into the lumen. Abluminally, they displayed extended slender cytoplasmic processes between islet endocrine cells. Administration of alloxan resulted to denser cytoplasm and a more prominent thickening of cytoplasmic processes of the intercalated duct cells, although the blood glucose levels did not show appreciable changes by the treatment. The intercalated duct epithelial cells appeared clearly as stellate cells. The lysosomes increased in size and number with passage of time after alloxan administration. The present findings may suggest that intercalated ducts are not only anatomically important as a structure passing through the islet but also play physiologically by protecting the islet endocrine cells.-KEY WORDS: alloxan, chicken, intercalated duct, pancreatic islet, stellate cell.

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Fine Structure of the Pancreatic Islets in Domestic Fowl with Special Reference to the Cell Type and Secretion

Cited by 18 publications

References 33 publications

Ultrastructure of endocrine pancreatic granules during pancreatic differentiation in the grass snake, Natrix natrix L. (Lepidosauria, Serpentes)

Ultrastructure of endocrine pancreatic granules during pancreatic differentiation in the grass snake, Natrix natrix L. (Lepidosauria, Serpentes)

Glucagon-like Peptide-1 Receptor Expression in the Pancreatic D Cells of Three Avian Species; White Leghorn Chickens, Northern Bobwhites, and Common Ostriches

Intercalated Duct Cells in the Chicken Pancreatic Islet with Special Reference to the Alloxan Administration.

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