“…it required a reducing agent for maximum activity, and it was inacti vated unless EDTA was present. If, as these data suggest, the active enzyme in Kohn's soluble proteolytic fraction (Kohn, 1969) (Resnick et al, 1968;Santa, 1969;Shafiq et al, 1969), streaming (Engel and Stonnington, 1974;Gauthier and Dunn, 19735 Santa, 1969;Stonnington and Engel, 1973), and disintegration and dis appearance (Johnson, 1969;Pellegrino and Franzini, 1963;Price et al, 1962;Tomanek and Lund, 1973). Based on a careful ultrastructural study of denervation atrophy in rat skeletal muscle, Pellegrino and Franzini (1963) (Lockshin and Beaulaton, 1974a;1974bj Schlaffino andHanzlikova, 1972).…”