Fine Structure and Histochemistry of the Choroid Plexus of the Teleost Leuciscus rutilus

Abstract

Analyses of the fine structure of the posterior choroid plexus in the teleost Leuciscus rutilus and the determination of the presence and function of the enzymes acid and alkaline phosphatases, ATPase and glucose‐6‐phosphatase confirm similarities between these epithelial cells and the saccus dorsalis and also with the epithelial cells of the choroid plexus found in mammals. The teleost plexus cells contain coated vesicles which are derived from the plasmalemma as well as from the Golgi complex. Moreover, they contain multivesicular bodies and Iysosomes. These organelles function in the absorption of substances from the cerebrospinal fluid and in the breakdown of these substances within the cells. The investigated enzymes play an important role in the secretion of electrolytes into the cerebrospinal fluid by active membrane transport.

Functional and Genetic Analysis of Choroid Plexus Development in Zebrafish

“…Historically, the CP of the third ventricle is often referred to as the dorsal sac or saccus dorsalis (Obermüller-Wilén, 1973). In the 1970s, comparative anatomical electron microscopy studies done in the teleost Leuciscus rutilus demonstrated that the dorsal sac and the hindbrain CP in the fourth ventricle are similar with one another, and also resemble the CP in mammals (Obermüller-Wilén, 1973). These studies found tight junction proteins and microvilli within the epithelia, and identified coated vesicles for transporting proteins (Obermüller-Wilén, 1973).…”

“…Teleosts have two identified CP structures, one in the third and one in the fourth ventricle . Historically, the CP of the third ventricle is often referred to as the dorsal sac or saccus dorsalis (Obermüller-Wilén, 1973). In the 1970s, comparative anatomical electron microscopy studies done in the teleost Leuciscus rutilus demonstrated that the dorsal sac and the hindbrain CP in the fourth ventricle are similar with one another, and also resemble the CP in mammals (Obermüller-Wilén, 1973).…”

“…In the 1970s, comparative anatomical electron microscopy studies done in the teleost Leuciscus rutilus demonstrated that the dorsal sac and the hindbrain CP in the fourth ventricle are similar with one another, and also resemble the CP in mammals (Obermüller-Wilén, 1973). These studies found tight junction proteins and microvilli within the epithelia, and identified coated vesicles for transporting proteins (Obermüller-Wilén, 1973). While the models discussed in the preceding paragraphs provide a snapshot or reconstruction of how the CP develops and functions; the development of this structure has seldom been visualized in a living system nor has it been genetically dissected.…”