Fine‐needle aspiration of metastatic melanoma with signet‐ring cell features

Abstract

An 80-year-old man who had a history of melanoma in the left anterior temple/scalp 2 years prior, that had been locally excised with a pathologic diagnosis of melanoma showing epithelioid and spindle cell morphology. He presented with a 0.9 Â 0.7 Â 0.4 cm 3 nodule in the left suboccipital intramuscular region that was radiologically suspicious for metastatic melanoma. A fine-needle aspiration (FNA) of the

Primary lipoblastic nerve sheath tumor in an inguinal lymph node mimicking metastatic tumor: a case report and literature review

“…They are distinguished by the coexistence of adipocytic and lipoblast-like signet-ring cell component, in the setting of a schwannoma background. Tumor cells displaying signet-ring or lipoblast-like morphology, however, are mostly associated with malignant epithelial neoplasms, mesotheliomas and melanomas (2)(3)(4)(5) and have been only rarely observed in soft tissue spindle cell tumors. Lipoblastic nerve sheath tumors have been identified in several anatomical sites, including the thigh, groin, shoulder, and retroperitoneum, yet there have been no reports of this tumor arising in lymph nodes.…”