Fine needle aspiration in the diagnosis and management of solid breast lesions

Ulanow, Robin M.; Galblum, Lawrence; Canter, Jerome W.

doi:10.1016/0002-9610(84)90345-3

Cited by 35 publications

(3 citation statements)

References 7 publications

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“…In our study the cytologic report correctly predicted the final histological results in 222 (95%) of the 234 cases. Nevertheless, the 3.4% incidence of false negative results in this study and 1.7-3% reported in the literature [ 10,21,22] emphasizes the fact that aspiration cytologic examination cannot be used as the sole criterion for evaluation of breast masses.…”

Section: Discussioncontrasting

confidence: 48%

Triple approach in the diagnosis of dominant breast masses: Combined physical examination, mammography, and fine‐needle aspiration

Kaufman

Shpitz

Shapiro

et al. 1994

Journal of Surgical Oncology

102

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In an attempt to reduce the number of breast biopsies done for benign breast disease in patients with breast lumps, we evaluated prospectively the sensitivity and specificity of the combination of three diagnostic modalities: clinical examination, mammography, and fine-needle aspiration cytologic examination (FNA). A total of 234 patients with a breast mass had a physical examination, a mammogram, and FNA, and were listed as malignant/suspicious or benign. All patients underwent a subsequent biopsy: 110 were found to have breast cancer, and 124 had a benign lesion. The sensitivity and specificity of the individual tests were as follows: 89% and 73%, respectively, for mammographic examination; 93% and 97% for FNA cytologic examination; and 89% and 60% for physical examination. For the combined triad of tests, the sensitivity was 100% and specificity 57%. All patients who had breast cancer had positive findings for malignancy in one or more of the diagnostic tests, i.e., 100% sensitively. All patients who had negative findings for malignancy in all three diagnostic tests had benign lesions, i.e., a negative predictive value of 100%. We conclude that breast masses can be diagnosed with a high degree of accuracy by combined physical, mammographic, and fine-needle aspiration cytologic examination. Patients in whom physical examination, mammography, and FNA were negative for malignancy can be safely observed, obviating the need for an open biopsy.

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Section: Discussioncontrasting

confidence: 48%

Triple approach in the diagnosis of dominant breast masses: Combined physical examination, mammography, and fine‐needle aspiration

Kaufman

Shpitz

Shapiro

et al. 1994

Journal of Surgical Oncology

102

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show abstract

“…4,5 The values obtained were compared analytically with those given in some published papers. 1,2,4,5,12,16,17,20,24,25 In 9 of the 11 series analyzed, 1,2,11,20,21,24,25 data concerning diagnostic ac-…”

Section: Methodsmentioning

confidence: 99%

Fine Needle Aspiration Biopsy of Breast Lesions and Histopathologic Correlation

Rocha

Nadkarni²,

Menezes³

1997

Acta Cytologica

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“…Consistent data are available to show that FNAC has a very high sensitivity and specificity – 87% and 99% respectively, as shown in Table 3 4,17–27 …”

Section: Accuracy Of Fine Needle Aspiration Cytologymentioning

confidence: 63%