Fine-needle aspiration in metastatic glioblastoma multiforme

Primary Intracranial Extraskeletal Mesenchymal Chondrosarcoma of the Brain in a Pediatric Patient: A Case Report and Review of Literature

“…In the pediatric age group, parenchymal lesions such as supratentorial primitive neuroectodermal tumor, high-grade non-Hodgkin's lymphoma, malignant hemangiopericytoma, or lesions originating from the base of the skull, such as chondrosarcoma at the skull base, embryonal rhabdomyosarcoma, or small cell osteosarcoma, should be the other differentials. 11 12 13 14 15 That is why, IHC is important to distinguish between those diagnoses, but no proper Immunohistochemistry (IHC) patterns have been identified till now, which is characteristic of IEMC. However, it is almost always positive for vimentin and S-100 and negative for synaptophysin, chromogranin, and EMA, but occasionally positive for GFAP (25% of the time).…”