Fine-needle aspiration cytology of pleuropulmonary blastoma: Case report and review of the literature

Abstract

This report describes the fine‐needle aspiration (FNA) cytology of a case of pleuropulmonary blastoma in a 3‐yr‐9‐mo‐old male. Pleuropulmonary blastoma is considered by most authors to be distinct from pulmonary blastoma and is a rare malignant tumor of the intrathoracic cavity. FNA smears were cellular with numerous small ovoid to spindled cells with oval to elliptical nuclei exhibiting finely granular chromatin and inconspicuous nucleoli. The cytoplasm was scant and cosinophilic with indistinct borders. Focal chondroid material and blastema‐like cells were noted. The differential diagnosis suggested by the cytologic findings included rhabdomysosarcoma, teratoma, neuroblastoma, malignant mesenchymoma, pleuropulmonary blastoma, and metastatic tumor. To our knowledge, this is the first report of the cytology of this tumor. Diagn. Cytopathol. 16:336–340, 1997. © 1997 Wiley‐Liss, Inc.

Quality-of-care initiative in patients treated surgically for perforated peptic ulcer

“…In another study, Kim et al described the cytologic findings of 17 sarcomas that were metastatic to the lung 13. The remaining reports were limited to individual case studies and small series 14–36. In the current study, we reported the findings of a series of 61 spindle cell lesions of the lung evaluated by FNA, with reference to the differential diagnosis, potential pitfalls, and appropriate use of ancillary studies.…”

Pleuropulmonary Blastoma: A Case Report

“…If PPB recurs in an individual patient, the type has often progressed to more advanced disease 4,10 . The diagnosis is made only on histologic evaluation of the excised mass; however, fine-needle aspiration cytology has been used to diagnose it 13,14,15,16 .…”

Pleuropulmonary blastoma: four cases

“…The diagnosis is made only on histologic evaluation of the excised mass. However, ®ne-needle aspiration cytology has been used to diagnose it [21,22]. Complete excision may not be possible if the tumour has invaded adjacent vital mediastinal structures, in which case partial excision or biopsy is carried out followed by chemotherapy.…”