2002
DOI: 10.1159/000326729
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Fine Needle Aspiration Cytology of Ductal Breast Carcinoma with Neuroendocrine Differentiation

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Cited by 20 publications
(21 citation statements)
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“…In particular, in the monotonous type, 17 of 28 cases exhibited neuroendocrine differentiation. This result confirmed our previous report and other studies [5,8,9,10,11]. Additionally, in the 19 cases of neuroendocrine differentiation, 15 were positive for E-cadherin immunohistochemically, which is different from lobular carcinoma [12,13].…”
Section: Discussionsupporting
confidence: 91%
“…In particular, in the monotonous type, 17 of 28 cases exhibited neuroendocrine differentiation. This result confirmed our previous report and other studies [5,8,9,10,11]. Additionally, in the 19 cases of neuroendocrine differentiation, 15 were positive for E-cadherin immunohistochemically, which is different from lobular carcinoma [12,13].…”
Section: Discussionsupporting
confidence: 91%
“…It is characterized by cellular monotony, nuclear palisading, pseudorosette formation, loss of cell cohesion, and abundant eosinophilic cytoplasm and nuclei with stippled (‘salt and pepper’) chromatin [49,57-59]. Nevertheless these features per se are not sensitive enough to rule in a diagnosis because they are inconsistently present [57].…”
Section: Discussionmentioning
confidence: 99%
“…With regard to the cytologic differential diagnosis, this entity must be distinguished from other subtypes of mucinous carcinoma, invasive micropapillary carcinoma, micropapillary/cystic hypersecretory DCIS, other mucocele‐like lesions, and even myxoid fibroadenoma. In contrast to the micropapillary variant, the neuroendocrine subtype of mucinous carcinoma tends to yield loosely dispersed tumor cells on fine‐needle aspiration biopsies 27, 28. The tumor cells show neuroendocrine cytology, including stippled chromatin, a plasmacytoid appearance, and granular eosinophilic cytoplasm.…”
Section: Discussionmentioning
confidence: 99%