“…[1][2][3][4][5][6][7][8] For the treatment of tuberculosis, the choice regimen of combined isoniazid and rifampin for 9-12 months is effective in 99% of patients, even with extrapulmonary tuberculosis. 1,3,5,8 In contrast, neoplastic empyema necessitatis, represented herein by two mesotheliomas and one small cell carcinoma, portends a grave prognosis with limited survival. Our patients survived 3, 7 and 5 months, respectively, with supportive, appropriate chemotherapeutic, and irradiation regimens.…”