Fine analysis of interaction mechanism of bioactive glass surface after soaking in SBF solution: AFM and ICP-OES investigations

Abstract

Bioactive glasses have the physical characteristics enabling them to be used in bone tissue engineering applications. However, the exact mechanism of the interactions between the glass surface and environment leading to the transition from the vitreous phase to the crystalline phase remains a subject of study. This work focuses on the growth of a calcium phosphate layer on the surface of the glass after immersion in a mineral solution, which mimics the mineral phase of human blood. The investigations use the Inductively Coupled Plasma and the Atomic Force Microscopy to establish the kinetic of crystallization, the kinetic of chemical reactivity and the surface transformations such as structure, texture and morphology of the bioactive glass. Obtained results show the progressive formation of a hydroxyapatite layer within 2 weeks. This crystal which is that of the bone belongs to the crystallographic structure within space group of P6 3/m. In addition, results show a decrease of the gradient of thickness which varies according to the immersion time from 7.5 µm to 2.8 µm and an increase of the homogeneity of the surface visible by the lowering of the gradient in the phase measurement from 60 Å to 15 Å.

Electrophoretic Deposition, Microstructure, and Selected Properties of Poly(lactic-co-glycolic) Acid-Based Antibacterial Coatings on Mg Substrate

“…Notably, the release of Si ions will have positive long-term bioactivity effects in bone regeneration, as well as antibacterial and angiogenic effects. 49 According to Rocton et al, 50 the concentration of Si ions increases due to the dissolution of MBGNs. In contrast, the concentration of Ca decreases due to the formation of calcium phosphate during the first 2 weeks ( Figure 4 A).…”

Dopamine-Assisted Modification of Polypropylene Film to Attain Hydrophilic Mineral-Rich Surfaces

“…Contrarily, the new apatite-related peaks were formed on all the PEI/PDA-modified samples, as seen clearly from Figure 6 b, suggesting the minerals` deposition, and remaining even after prolonged washing. Herein, the extremely intensive and broad peak at 1024 cm −1 is attributed to the phosphate asymmetrical stretching [ 19 ], as well as to the Si-O-Si symmetrical stretching of the hydrolysed TEOS [ 26 , 30 ], at 1296 cm −1 to the P-OH bending, at 1455 cm −1 to the carbonyl groups, and the broad band at ~3500 cm −1 corresponded to the stretching vibrations of the −OH groups [ 19 ]. The small peak at ~875 cm −1 is related to the C-O vibrations of hydroxyapatite and the intensified peak at ~1610 cm −1 to O-H stretching [ 17 ].…”

Additive Manufacturing of Bioactive Glass and Its Polymer Composites as Bone Tissue Engineering Scaffolds: A Review

“…The emergence of bioactive glass (BG) has ignited research interest globally, as evidenced by the continuous growth in the number of publications since 1971. Much effort has been made to unveil the mechanism of bioactivity [ 9 , 12 , 13 ], the relationships among compositional, structural, and physiochemical properties [ 14 , 15 , 16 ], novel glass synthesis methods [ 17 , 18 , 19 ], and the functionalization of BG [ 20 , 21 , 22 ], with the aim of achieving safer and more effective bone tissue regeneration induced by BG scaffolds.…”