Findings of Esophagogastroduodenoscopy in Patients Suspected of Upper Gastrointestinal Bleeding Referred to the Main Endoscopy Unit at King Fahad Specialist Hospital

Alatawi, Abdallah; Aljohani, Wejdan; Aljayani, Rabab T.; Alblowi, Yassmeen; M, Yousuf; Almutairi, Hadeel

doi:10.7759/cureus.11862

Cited by 3 publications

(4 citation statements)

References 25 publications

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“…10% had history of NSAIDS use and 5% of them were on low dose aspirin therapy. 6 Hematemesis and melena were the most common presenting complains in numerous studies, 1,10,12,17 which are consistent with our findings.…”

Section: Discussionsupporting

confidence: 91%

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Study of Endoscopic Findings in First Episode of Upper Gastrointestinal Bleeding

Adhikari

Mandal²

2021

J Adv Intern Med

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Background and Aims: Upper gastrointestinal bleeding (UGIB) is one of the most common and grave emergencies encountered in Emergency department in Tertiary health care centre in our country. Upper endoscopy has a crucial role in the diagnosis and treatment of upper gastrointestinal bleeding. The aim of this study is to assess the endoscopic findings in patients presenting with first episode of UGIB. Methods: This was a hospital based cross sectional study of patients with haematemesis, melena or both who underwent UGI endoscopy at Bir Hospital during January 2019 to January 2020. Patient demographics, site and nature of lesions and risk factors for bleeding were analyzed. Results: Among 72 enrolled patients 48 (66.67 %) were male and 24 (33.3 %) were female. Haematemesis 27% was the most common presenting complain followed by melena 25.5% and fainting/ dizziness 22.5%. Endoscopy was done in all cases and gastric ulcer disease 27.8% was the commonest cause of first episode of UGI bleeding followed by variceal bleeding, gastric erosion and duodenal ulcer, 25%, 16.7%, 12.5% respectively. Conclusions: Peptic ulcer disease was the most common cause of first episode of UGI bleeding in our context. Among peptic ulcer diseases gastric ulcer was more common than duodenal ulcer. Haematemesis and melena were the commonest clinical presentation of UGI bleeding.

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Section: Discussionsupporting

confidence: 91%

“…Similarly male predominance was found in various studies in Nepal and abroad with 80.7% , 72%, 67%, 64% respectively. 8,10,11,12 Hower ever few studies also showed female predominance in patients with UGI Bleeding. A study done from Nepal had 79% of females with UGI bleeding.…”

Section: Discussionmentioning

confidence: 98%

Study of Endoscopic Findings in First Episode of Upper Gastrointestinal Bleeding

Adhikari

Mandal²

2021

J Adv Intern Med

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“…Our results confirmed this, with 59% of patients presenting with as melena and 21% of patients with melena and haematemesis simultaneously. Ar ecent study showed that the most frequent nonvariceal findings on proximal endoscopy were duodenal ulcers, representing about two-thirds of cases, followed by antral gastropathy, gastric ulcers and duodenal/gastric mass, with GERD and Mallory Weiss syndrome much less frequent (9). Our results are in accordance with this study, confirming that duodenal ulcers the leading cause of gastrointestinal bleeding, followed by gastric ulcers, hemorrhagic erosions, neoplasm and GERD.…”

Section: Discussionsupporting

confidence: 90%

Characteristics of Patients with Nonvariceal Upper Gastrointestinal Bleeding - Are We Underestimating Gastroprotection during NSAIDs Therapy?

Čustović

Saray

Ćato-Mehmedbašić

et al. 2021

ama

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Objective. The aim of our study was to determine the etiological factors, treatment and outcome of patients with non-variceal bleeding from upper gastrointestinal tract.Materials and Methods. This study enrolled 200 patients admitted to Sarajevo University Clinical Center with signs and symptoms of upper gastrointestinal bleeding, from January 2019 to July 2020. All patients had undergone gastroscopy, confirming the cause of gastrointestinal bleeding. Clinical and laboratory data were collected retrospectively, including previous non-steroid antiinflammatory drugs (NSAIDs) and anticoagulant therapy, comorbidities, risk factors, as well as endoscopic findings, laboratory findings, treatment and clinical follow-up.Results. The majority of patients were men (59%) with an average age of 53±6 years. Duodenal and gastric ulcers were the most common cause, followed by other etiologies. In our study, previous NSAIDs therapy had been registered in 29.5% of patients, anticoagulants in 8%, and proton pump inhibitors (PPI) in 2.9% of patients. Endoscopic intervention was required in 34% of patients. The need for transfusion occurred in 44.5% of cases. Rebleeding during hospitalization was observed in 7.5% of patients, mortality in 1.5% and surgery in 3% of patients.Conclusion. The patients admitted to our hospital with symptoms of acute nonvariceal upper gastrointestinal bleeding were elderly, predominantly males, with significant comorbidities and a higher incidence of NSAID use. Gastroprotection is underutilized during NSAID treatment in patients with other coexisting risk factors,with a low rate of concomitant use of PPI during NSAIDs therapy. Endoscopic therapy, together with PPI, significantly reduces rebleeding rates, mortality and the number of emergency surgical interventions.

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“…Although peptic ulcer bleed and portal hypertension-related bleed accounts for majority of the case, non-variceal nonulcer bleeding accounts for 34-64% of all presenting cases of non-variceal UGIB in various series. [26][27][28] These include a large variety of uncommon reasons which contribute to UGB and might become reasons for misdiagnosis and sometimes lead to fatal consequences. Among this special group of patients, various pathologies found in our study were Dieulafoys lesion (0.61%), Mallory-Weiss lesions (0.38%), GI stromal tumor (0.20%), gastric polyps (0.80%), ampullary tumor (0.19%) and hemobilia (0.11%).…”

Section: Discussionmentioning

confidence: 99%

Epidemiological and endoscopic profile of patients with upper gastrointestinal bleeding at a tertiary care center in Northern India : A retrospective analysis of twenty years

et al. 2023

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Background: Upper gastrointestinal (UGI) bleed is a common emergency presenting to emergency departments all over the world. Since the spectrum of UGI bleeding varies from region to region, it is important to know the profile of UGI bleed for proper management approach. Here, we present the endoscopic profile of UGI bleed presenting to a tertiary care setting in Northern India. Aims and Objectives: This study aimed to determine the epidemiological and endoscopic profile of patients with UGI over twenty years. Materials and Methods: The retrospective and observational study included adults patients (above 18 years of age) of either gender, who presented with UGI bleed at our center over a twenty year period from January 1999 to December 2018. Results: A total of 13418 patients with UGI bleed had esophagogastroduodenoscopy (EGD) done on them during this period. Six thousand one hundred and thirty-two patients (45.7%) were females while 7285 were males (54.3%). Mean age was 46±16 years. The common endoscopic findings were pepticulcer disease in 7508 (48.25%) patients followed by erosive gastritis in 2305 (14.81%), UGI tract malignancy in 1152 (7.8%). Variceal bleed was seen in 900 (5.77%) patients. Conclusion: Peptic ulcer related bleed is the most common cause of UGI bleed in our center. Portal hypertension is relatively less frequent a cause of UGI bleed in our place.

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Findings of Esophagogastroduodenoscopy in Patients Suspected of Upper Gastrointestinal Bleeding Referred to the Main Endoscopy Unit at King Fahad Specialist Hospital

Cited by 3 publications

References 25 publications

Study of Endoscopic Findings in First Episode of Upper Gastrointestinal Bleeding

Study of Endoscopic Findings in First Episode of Upper Gastrointestinal Bleeding

Characteristics of Patients with Nonvariceal Upper Gastrointestinal Bleeding - Are We Underestimating Gastroprotection during NSAIDs Therapy?

Epidemiological and endoscopic profile of patients with upper gastrointestinal bleeding at a tertiary care center in Northern India : A retrospective analysis of twenty years

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