Finding the hidden faces: Schizophrenic patients fare worse than healthy subjects

Zivotofsky, Ari Z.; Oron, Liron; Hibsher-Jacobson, Liron; Weintraub, Yelena; Strous, Rael D.

doi:10.1016/j.neuropsychologia.2008.02.024

Cited by 11 publications

(9 citation statements)

References 20 publications

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“…Impaired affective and non-affective face perception in schizophrenia has been widely reported (Butler et al 2008; Chen 2011; Chen et al 2008; Marwick & Hall 2008; Phillips & David 1995; Silverstein et al 2010; Zivotofsky et al 2008). Yet it is not completely understood how the processing of facial information is related to clinical dimensions in this mental disorder.…”

Section: Discussionmentioning

confidence: 99%

Distinct facial processing in schizophrenia and schizoaffective disorders

Chen¹,

Cataldo²,

Norton³

et al. 2012

Schizophrenia Research

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Although schizophrenia and schizoaffective disorders have both similar and differing clinical features, it is not well understood whether similar or differing pathophysiological processes mediate patients’ cognitive functions. Using psychophysical methods, this study compared the performances of schizophrenia (SZ) patients, patients with schizoaffective disorder (SA), and a healthy control group in two face-related cognitive tasks: emotion discrimination, which tested perception of facial affect, and identity discrimination, which tested perception of non-affective facial features. Compared to healthy controls, SZ patients, but not SA patients, exhibited deficient performance in both fear and happiness discrimination, as well as identity discrimination. SZ patients, but not SA patients, also showed impaired performance in a theory-of-mind task for which emotional expressions are identified based upon the eye regions of face images. This pattern of results suggests distinct processing of face information in schizophrenia and schizoaffective disorders.

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Section: Discussionmentioning

confidence: 99%

Distinct facial processing in schizophrenia and schizoaffective disorders

Chen¹,

Cataldo²,

Norton³

et al. 2012

Schizophrenia Research

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show abstract

“…Two previous studies have shown that schizophrenia patients are less accurate than healthy controls at detecting faces (Chen et al, 2008; Zivotofsky et al, 2008). While this result was replicated in the present study, our findings also indicate that a generalized deficit may have played a role in poor patient performance on this task (refer to p. 10 for a review of reasons).…”

Section: Discussionmentioning

confidence: 96%

“…Schizophrenia patients are deficient at face perception tasks, including face detection (Chen et al, 2008; Zivotofsky et al, 2008), facial identity discrimination (Shin et al, 2008; Chen et al, 2009), and facial emotion recognition (Walker et al, 1984; Heimberg et al, 1992). The way in which these face perceptual impairments impact the social lives of persons with schizophrenia is a current area of investigation (e.g.…”

Section: Introductionmentioning

confidence: 99%

A female advantage in basic face recognition is absent in schizophrenia

McBain

Norton

Chen

2010

Psychiatry Research

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Healthy females outperform males on face recognition. Relative to healthy individuals, schizophrenia patients are impaired on face perception tasks. Yet, it is unclear whether the female advantage found in healthy controls is preserved in females with schizophrenia. In the present study, we compared male and female patients and healthy controls on two basic face perception tasks – detection and identity discrimination. In the detection task, subjects located an upright or inverted line-drawn face (or a tree) embedded within a larger line-drawing. In the identity discrimination task, subjects determined which of two side-by-side face images matched an earlier presented face image. Healthy females were significantly more accurate than healthy males on face detection, but not on identity discrimination. However, female patients were not more accurate than male patients on either task. On both upright face detection and face identity discrimination, healthy controls significantly outperformed patients. Patients’ performance on face detection was closely associated with tree detection and IQ scores, as well as level of psychosis. This pattern of results suggests that a female advantage in basic face perception is no longer available in schizophrenia, and that this absence may be related to a generalized deficit factor, which acts to level performance across sexes, and putative changes in sex-related neurobiological differences associated with schizophrenia.

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“…Along these same lines, several other studies also found compromised face-inversion effects in patients (37–39) whereas others found no such effects (40, 41). It has also been reported that the detection of human face images, as compared to animal face images, were specifically impaired in schizophrenia patients (42). These investigations suggest that the processing of facial configuration information, relative to the processing of non-face information, is compromised in schizophrenia and future investigations explore the conditions under which face-specific processing might be implicated.…”

Section: Visual and Cognitive Processing Of Face Stimulimentioning

confidence: 97%

Visual and Associated Affective Processing of Face Information in Schizophrenia: A Selective Review

Chen

Ekstrom

2015

CPSR

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Perception of facial features is crucial in social life. In past decades, extensive research showed that the ability to perceive facial emotion expression was compromised in schizophrenia patients. Given that face perception involves visual/cognitive and affective processing, the roles of these two processing domains in the compromised face perception in schizophrenia were studied and discussed, but not clearly defined. One particular issue was whether face-specific processing is implicated in this psychiatric disorder. Recent investigations have probed into the components of face perception processes such as visual detection, identity recognition, emotion expression discrimination and working memory conveyed from faces. Recent investigations have further assessed the associations between face processing and basic visual processing and between face processing and social cognitive processing such as Theory of Mind. In this selective review, we discuss the investigative findings relevant to the issues of cognitive and affective association and face-specific processing. We highlight the implications of multiple processing domains and face-specific processes as potential mechanisms underlying compromised face perception in schizophrenia. These findings suggest a need for a domain-specific therapeutic approach to the improvement of face perception in schizophrenia.

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Finding the hidden faces: Schizophrenic patients fare worse than healthy subjects

Cited by 11 publications

References 20 publications

Distinct facial processing in schizophrenia and schizoaffective disorders

Distinct facial processing in schizophrenia and schizoaffective disorders

A female advantage in basic face recognition is absent in schizophrenia

Visual and Associated Affective Processing of Face Information in Schizophrenia: A Selective Review

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