Finding a new drug and vaccine for emerging swine flu: What is the concept?

Abstract

Influenza is a well known infection of the respiratory system. The main clinical manifestations of influenza include fever, sore throat, headache, cough, coryza, and malaise. Apart from the well known classical influenza, there are also groups of influenza virus infections that are called "atypical infection". These infections are usually due to a novel influenza virus infection. In early 2009, an emerging novel influenza originating from Mexico called swine flu was reported. The World Health Organization noted a level VI precaution, the highest level precaution possible, for this newest influenza virus infection. As of June 2009, it is not known if this disease will be successfully controlled. Finding new drugs and vaccine for the emerging swine flu is still required to cope with this emerging worldwide problem.

Swine flu vaccine: Present status

“…6,7 Continuous infections, up to several thousand cases, since its first emerging in April 2009 confirm the seriousness of the problem. It is also no doubt that there is no country that succeeds in getting rid of or completely controlling the infection.…”

“…In addition, there is evidence that some elders have already circulating protective immunity to swine flu. 6,7 Of interest, this might imply that there might be an emerging of swine flu in the previous days, many decades ago when there is no available molecular technique to sequence the exact viral sequence, and the elder ones who have protective immunity might be the survivors from that outbreak. 8 Nevertheless, most of the populations in the world have no protective immunity to swine flu.…”

Swine flu vaccination for patients with cancers

“…In addition, based on the pandemic mode of development, the complete data on vaccine study cannot be expected and postmarketing surveillance is strongly recommended. [17] Nevertheless, it is believed that the new swine flu vaccine is similarly effective and safe.…”

Emergence of swine flu in Andhra Pradesh: Facts and future

“…The reports indicated that the 1918 H1N1 pandemic caused the death of 20-50 million people worldwide and current H1N1 pandemic is feared of resulting into the similar effect [5]. The World Health Organization (WHO) announced the level 6 precaution, the highest precaution level, for the 2009 infl uenza pandemic [6]. It was discovered that the new H1N1 strain evolved as a result of strong purifying selection, widely different from the strains that are reported during recent past few years, but surprisingly it is closely related to the ancient strain reported in 1918 [7].…”