Finding a needle in a haystack: Endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic masses in the setting of chronic pancreatitis

Xie, Chencheng; Bohy, Kimberlee; Abdallah, Mohamed; Patel, Bhaveshkumar; Nelson, Morgan E.; Bleeker, Jonathan; Askeland, Ryan W.; Abdullah, Ammar; Aloreidi, Khalil; Kiani, Rabia; Atiq, Muslim

doi:10.20524/aog.2020.0484

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2021

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“…An erroneous diagnosis can be due to the presence of a focal hypoechoic mass, vascular involvement, or local mass extension to surrounding structures [ 6 ]. It is challenging to differentiate PAC from chronic pancreatitis (CP) based on cytology, as both exhibit large nuclei and degenerative vacuoles [ 7 ]. In PAC, cellular features include epithelial cell neoplasm with glandular differentiation, which can range from infiltrating single cells with mucin production to solid sheets of neoplastic cells.…”

Section: Discussionmentioning

confidence: 99%

A Dangerous Mimic: Chronic Pancreatitis Masquerading As Pancreatic Adenocarcinoma

Li¹,

Salik²

2021

Cureus

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Pancreatic adenocarcinoma (PAC) is the most common form of pancreatic cancer in adults, although extremely rare before the age of 40 years. It is known that the cytology of chronic pancreatitis can mimic pancreatic adenocarcinoma. We present a case of a 13-year-old male with chronic pancreatitis that was misdiagnosed as PAC. The patient subsequently underwent a Whipple procedure, highlighting the importance of a correct diagnosis prior to undergoing invasive surgical procedures.

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Section: Discussionmentioning

confidence: 99%