Finasteride Treatment of Female Pattern Hair Loss

Iorizzo, Matilde; Vincenzi, Colombina; Voudouris, Stylianos; Piraccini, Bianca Maria; Tosti, Antonella

doi:10.1001/archderm.142.3.298

Cited by 111 publications

(72 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Special attention is also given to the use of a contraceptive pill or hormonal replacement therapy, since gestagens with proandrogenic effect may exacerbate hair loss and are consequently contraindicated in these women. Some authors eventually recommend the use of antiandrogen therapy, such as cyproterone acetate [5], spironolactone [5, 6] or finasteride [7], though there exists controversy on this issue [8,9,10]. Nevertheless, a number of women complain of recurrent hair loss, despite at times successful therapy.…”

Section: Introductionmentioning

confidence: 99%

Seasonality of Hair Shedding in Healthy Women Complaining of Hair Loss

2009

View full text Add to dashboard Cite

Background: A number of otherwise healthy women with or without clinical alopecia complain of recurrent hair loss, presumably reflecting seasonality in the growth and shedding of hair. Objective: To test the hypothesis that periodicity in hair shedding reflects seasonal changes in human hair growth. Methods: Retrospective case study over a period of 6 years of apparently healthy women with the complaint of hair loss. All underwent biochemical investigations, and trichograms were made. Results: After exclusion of patients with a disease or on drugs known to cause hair loss, 823 women remained. Analysis of trichograms demonstrated annual periodicity in the growth and shedding of hair, manifested by a maximal proportion of telogen hairs in summer. A second peak seems to exist, though it is less pronounced, in spring. The telogen rates were lowest in late winter. Conclusions: These results confirm the findings of former authors who have indicated seasonal changes in human hair growth, though this is the first study performed systematically in a representative number of women.

show abstract

Section: Introductionmentioning

confidence: 99%

Seasonality of Hair Shedding in Healthy Women Complaining of Hair Loss

2009

View full text Add to dashboard Cite

show abstract

“…In two uncontrolled studies, finasteride (Propecia) at a minimum dose of 2.5 mg per day appeared to have a benefit for women with FPHL [32]. However, in a controlled trial involving postmenopausal women with FPHL, treatment with it at a dose of 1 mg per day was not significantly better than placebo [33].…”

Section: Anti-androgen Therapiesmentioning

confidence: 97%

Hair: A Review of Prominent Scalp Hair Changes throughout a Females’ Life

Aly¹

2014

Pigmentary Disorders

View full text Add to dashboard Cite

“…Regarding the use and of finasteride in women, its efficacy is not well-established and is used as an off-label treatment of 2.5-5mg/day [89][90][91]. Two RCT have demonstrated that the use of 1mg/day is not effective in women.…”

Section: Alpha Reductase Inhibitorsmentioning

confidence: 99%

Androgenetic Alopecia: a Review and Emerging Treatments

Alves¹

2017

CRDOA

View full text Add to dashboard Cite

Androgenetic Alopecia (AGA) is the most common noncicatricial alopecia that leads to the progressive miniaturization of the hair follicle. Scalp terminal hairs are converted into vellus hairs, primarily due to two factors: genetic predisposition and hormonal stimulation.The incidence and prevalence of AGA increases with age. The onset of AGA is gradual, and when this pathology progresses, the anagen phase shortens and the telogen phase remains constant. The shedding area varies from patient to patient and is usually most marked at the vertex in men, while women with AGA generally lose hair diffusely over the crown.Topical minoxidil and oral finasteride (5-alpha-reductase type II inhibitor) are the gold-standard therapies for AGA and are currently the only Food and Drug Administration (FDA)-approved drugs for the treatment of AGA.The currently available treatments for AGA are sometimes perceived as having limited effectiveness; therefore, the identification of new therapies for this pathology is of utmost importance.This article aims to review the pathogenesis, diagnosis of AGA and all the new emerging treatments for this entity in order to prevent its progression and improve the results of this pathology.

show abstract

Finasteride Treatment of Female Pattern Hair Loss

Cited by 111 publications

References 18 publications

Seasonality of Hair Shedding in Healthy Women Complaining of Hair Loss

Seasonality of Hair Shedding in Healthy Women Complaining of Hair Loss

Hair: A Review of Prominent Scalp Hair Changes throughout a Females’ Life

Androgenetic Alopecia: a Review and Emerging Treatments

Contact Info

Product

Resources

About