Globalization and industrialization have exposed the world to the exacerbating issue of sustainability. With the occurrences of climate related extreme events increasing the world over in the last decade, climate change has come to be recognized as the most profound concern staring in the face of mankind. There have been many separate studies addressing climate change and an equally good number of research in the domain of quality of life. But there is a dearth of research linking climate variability and quality of life. Climate uncertainties have led to loss of lives. Settlements and employments, material living conditions, physical and economic security, natural environment, health, basic rights, and social exchanges among communities stand impacted. All of these metrics are important determinants of quality of life (QoL). Also, alarming is the fact that QoL indicators remain poorly connected to climate change related concerns. This is an important research gap and calls for urgent attention.