Financial requirements of immunisation programmes in developing countries: a 2004–2014 perspective

Peny, Jean-Michel; Gleizes, Olivier; Covilard, Jean-Pierre

doi:10.1016/j.vaccine.2005.04.044

Cited by 29 publications

(8 citation statements)

References 4 publications

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“…Cough was the most commonly reported first symptom of illness (103, 74%) and one caretaker reported that difficult breathing was the first symptom to be recognised. The first symptom had been noted a median of 7 days before arrival at hospital (interquartile range [4][5][6][7][8][9][10][11][12][13][14]. Fever had reportedly been noted by 88% of caretakers a median of 3 days previously.…”

Section: Resultsmentioning

confidence: 99%

Care-seeking in the development of severe community acquired pneumonia in Ugandan children

Hildenwall

Nantanda

Tumwine

et al. 2009

Annals of Tropical Paediatrics

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Although the majority of caretakers were able to recognise the key symptoms of pneumonia, they did not respond with any immediate care-giving action. Since progression from first recognition of pneumonia symptoms to severe disease is rapid, management guidelines regarding timing of care-seeking need to be clearly defined. The reason why children who sought health facility care failed to improve should be investigated. Meanwhile, there is a need to increase caretakers' and health workers' awareness of the urgency to act promptly when key pneumonia symptoms are observed.

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Section: Resultsmentioning

confidence: 99%

Care-seeking in the development of severe community acquired pneumonia in Ugandan children

Hildenwall

Nantanda

Tumwine

et al. 2009

Annals of Tropical Paediatrics

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“…While prevention of ARIs is obviously better than cure, the necessary public health interventions, such as immunisation, housing and sanitation, are expensive and take time 9. Until then, ARI mortality reduction is dependent on case detection and treatment 10.…”

Section: Introductionmentioning

confidence: 99%

Can we distinguish pneumonia from wheezy diseases in tachypnoeic children under low-resource conditions? A prospective observational study in four Indian hospitals

Gowraiah

Awasthi

Kapoor³

et al. 2014

Archives of Disease in Childhood

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Current tachypnoea-based algorithms significantly overdiagnose pneumonia in children and underdiagnose wheezy diseases. Diagnostic accuracy can be improved by various combinations of clinical variables, but the best single diagnostic predictor is auscultation. Simple criteria can also be defined that reliably detect which tachypnoeic children are at high risk of death or deterioration. Management plans based on these protocols could reduce unnecessary antibiotic use, improve the management of wheezy diseases and reduce mortality by earlier identification of high-risk children.

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“…The fact is that, in light of growing health inequities aggravated by worsening wealth distribution, the need for vaccines in poor and developing countries has never been more pressing (Peny, Gleizes, & Covilard, 2005). The development of new, safe, and affordable vaccines and new vaccine delivery technology for infectious diseases in developing countries is crucial for the survival of hundreds of millions of people, especially children (Global Alliance for Vaccine Initiatives [GAVI], 2007).…”

Section: Resultsmentioning

confidence: 99%

A model of regulatory burden in technology diffusion: The case of plant-derived vaccines

Castle

Kumagai

Cloutier³

et al. 2008

PICMET '08 - 2008 Portland International Conference on Management of Engineering &Amp; Technology

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Plant-derived vaccines may soon displace conventional vaccines. Assuming there are no major technological barriers undermining the feasibility of this innovative technology, it is worthwhile to generate quantitative models of regulatory burden of producing and diffusing plant-derived vaccines in industrialized and developing countries. A dynamic simulation model of technology diffusion-and the data to populate it-has been generated for studying regulatory barriers in the diffusion of plant-derived vaccines. The role of regulatory burden is evaluated for a variety of scenarios in which plant-derived vaccines are produced and diffused. This model relates the innovative and conventional vaccine technologies and the effects of the impact of the uptake of the innovative technology on mortality and morbidity. This case study demonstrates how dynamic simulation models can be used to assess the long-term potential impact of novel technologies in terms of a variety of socio-economic indicators.

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Financial requirements of immunisation programmes in developing countries: a 2004–2014 perspective

Cited by 29 publications

References 4 publications

Care-seeking in the development of severe community acquired pneumonia in Ugandan children

Care-seeking in the development of severe community acquired pneumonia in Ugandan children

Can we distinguish pneumonia from wheezy diseases in tachypnoeic children under low-resource conditions? A prospective observational study in four Indian hospitals

A model of regulatory burden in technology diffusion: The case of plant-derived vaccines

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