Final Safety Results of a Phase 1 Clinical Trial of Afatinib in Combination With Docetaxel and Postoperative Radiation Therapy for High-Risk Squamous Cell Carcinoma of the Head and Neck
Abstract:setting have yet to be examined. The purpose of our study is to determine whether NAC followed by CCRT provides an overall survival (OS) benefit, particularly among high-risk patients. Materials/Methods: We queried the national cancer database for patients with NPC and limited the initial 13,929 patients to those treated with either NAC followed by CCRT or CCRT alone; defining NAC followed by CCRT as chemotherapy initiation 21 days prior to RT initiation and CCRT as initiation 20 days prior to and 36 days afte… Show more
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