Filter Construction and Design

Jornitz, Maik W.

doi:10.1007/b104244

Cited by 7 publications

(4 citation statements)

References 2 publications

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“…via heating, [23]) to give permanence to the shape and structure of the pleated filter. Several key design factors used in characterization of pleated filters have been identified in the literature, and a detailed description can be found in, e.g., [24], [8] and [23]. In our study, we focus on pleated filters with high pleat packing density (PPD), in which it is assumed that air gaps between adjacent pleats are negligible.…”

Section: Introductionmentioning

confidence: 99%

Modeling and design optimization for pleated membrane filters

et al. 2020

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Pleated membrane filters, which offer larger surface area to volume ratios than unpleated membrane filters, are used in a wide variety of applications. However, the performance of the pleated filter, as characterized by a flux-throughput plot, indicates that the equivalent unpleated filter provides better performance under the same pressure drop. Earlier work (Sanaei & Cummings 2016) used a highly-simplified membrane model to investigate how the pleating effect and membrane geometry affect this performance differential. In this work, we extend this line of investigation and use asymptotic methods to couple an outer problem for the flow within the pleated structure to an inner problem that accounts for the pore structure within the membrane. We use our new model to formulate and address questions of optimal membrane design for a given filtration application. *

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Section: Introductionmentioning

confidence: 99%

Modeling and design optimization for pleated membrane filters

et al. 2020

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“…This method is suitable for filtering solutions which are difficult to filter and can be used in studies of solubility, dose homogeneity, etc. However, they are mainly used at the point of performing infusions or injections, to exclude the possibility of introducing various inclusions [21].…”

Section: Use Of Membrane Filters 35mentioning

confidence: 99%

Use of Membrane Filters in Production Technology for Sterile Drugs

et al. 2016

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Filtration is one of the methods on which all the world's chemical-pharmaceutical industries depend. This technological method is used for the sterilization of labile drugs and to provide them with the required properties. As a result of the introduction of strict GMP rules, most current plants use membrane filtration. We review here the main criteria used for selecting material for sterilizing filtration and provide examples of drugs whose manufacture uses this method.

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“…Äàííûé ñïîñîá ïîäõîäèò äëÿ ôèëüòðîâàíèÿ òðóäíî ôèëüòðóåìûõ ðàñòâî-ðîâ, ìîaeåò èñïîëüçîâàòüñÿ äëÿ ïðîâåäåíèÿ èññëåäîâàíèé ïî ðàñòâîðèìîñòè, îäíîðîäíîñòè äîçèðîâàíèÿ è ò.ä. Îä-íàêî â îñíîâíîì èõ èñïîëüçóþò â ìîìåíò ïðîâåäåíèÿ èí-ôóçèè èëè èíúåêöèè ïàöèåíòó, òåì ñàìûì èñêëþ÷àÿ âîç-ìîaeíîñòü ïîïàäàíèÿ ðàçëè÷íûõ âêëþ÷åíèé [21].…”

Section: ñâîéñòâà è õàðàêòåðèñòèêè ìàòåðèàëîâ äëÿ ñòåðèëèçóþùåé ôèëüòunclassified

Применение Мембранных Фильтров В Технологии Получения Стерильных Лекарственных Препаратов

Гулякин¹,

Николаева²,

Санарова³

et al. 2016

Хим.-фарм. ж.

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Îäíèì èç ìåòîäîâ, áåç êîòîðîãî íå îáõîäèòñÿ íè îäíî èç ñóùåñòâóþùèõ â ìèðå ñîâðåìåííûõ õèìèêî-ôàðìàöåâòè÷åñêèõ ïðîèçâîäñòâ, ÿâëÿåòñÿ ôèëüòðàöèÿ. Äàííûé òåõíîëîãè÷åñêèé ìå-òîä ïðèìåíÿåòñÿ äëÿ ñòåðèëèçàöèè ëàáèëüíûõ ëåêàðñòâåííûõ ïðåïàðàòîâ è ïðèäàíèÿ èì íå-îáõîäèìûõ ñâîéñòâ. Ââåäåíèå ñòðîãèõ ïðàâèë GMP ïðèâåëî ê òîìó, ÷òî â íàñòîÿùåå âðåìÿ âñå ñóùåñòâóþùèå ïðåäïðèÿòèÿ â áîëüøèíñòâå ñëó÷àåâ ðàáîòàþò ñ ìåìáðàííûìè ôèëüòðà-ìè. Â ïðåäñòàâëåííîì îáçîðå ðàññìîòðåíû îñíîâíûå êðèòåðèè, êîòîðûå ïðèìåíÿþòñÿ ïðè âûáîðå ìàòåðèàëà äëÿ ñòåðèëèçóþùåé ôèëüòðàöèè è ïðèâåäåíû ïðèìåðû êîíêðåòíûõ ëåêàð-ñòâåííûõ ïðåïàðàòîâ, ïðè ïðîèçâîäñòâå êîòîðûõ èñïîëüçóåòñÿ äàííûé ìåòîä.Êëþ÷åâûå ñëîâà: ñòåðèëèçóþùàÿ ôèëüòðàöèÿ; ìåìáðàííûå ôèëüòðû; êàñêàäíàÿ ýêñòðó-çèÿ; ëèïîñîìû.

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Filter Construction and Design

Cited by 7 publications

References 2 publications

Modeling and design optimization for pleated membrane filters

Modeling and design optimization for pleated membrane filters

Use of Membrane Filters in Production Technology for Sterile Drugs

Применение Мембранных Фильтров В Технологии Получения Стерильных Лекарственных Препаратов

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