“…15 Adverse reactions to CSF were reported in 13 patients. 3,12,13,15,48,61 They included skin rash (3 with GM-CSF, 12 1 with G-CSF 3 ), headache (2 with G-CSF), 15 acute respiratory distress syndrome (2 with G-CSF), 3 acute respiratory distress syndrome with pulmonary edema (1 with G-CSF), 3 fever (1 with GM-CSF), 48 mild bone pain (1 with G-CSF), 15 and musculoskeletal pain in the legs and arms (1 with GM-CSF). 61 A patient treated with G-CSF experienced polyarthralgia, swelling at bilateral elbow joints, and flare-up of arthritis.…”