“…For example, the number of patients required to demonstrate a 50 % RR difference with a baseline hernia recurrence rate of 2 %, with a significance level of 95 % and power of 80 % would be at least 4,534 patients [37]. Second, although the reporting of chronic groin pain did not demonstrate significant heterogeneity, the definition of chronic groin pain in terms of when and how it was measured was variable among the studies, as were the types of mesh used, which can have a bearing on chronic groin pain [14][15][16][17][18][19][20][21][22][23]. Third, when considering postoperative hematoma, some of the common risk factors for hematoma were not mentioned in the included randomized control trials, such as use of antiplatelet and anticoagulation agents.…”