Figure S4 from Antisecretory Factor–Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma

Abstract

<p>Fig. S4. AF treatment results in no changes in body weight for mice xenografted with GBM43 cells and resulted in complete tumor regression in an EGFRvIII-expressing GBM allograft model. (A, B) SPC or Salovum treatment had no effect on body weight in GBM43 xenografts (n=7 for control, n=10 for SPC, and n=5 for Salovum). (C) SPC treatment resulted in complete tumor regression in 5/6 FVBn mice allografted with EGFRvIII and mCherry-expressing mouse GBM cells (dotted line; tumor border). Scale bar 2 mm.</p>