“…During this study, we went through different scientific NLP and IR approaches, which have been proposed for text and biomedical image mining e.g. ImageJ ( 30 ), CellProfiler ( 31 ), CellPloc ( 32 ), Vaa3D ( 33 ), Icy ( 34 ), Konstanz Information Miner ( KNIME ) ( 35 ), Fiji ( 36 , 37 ), Framework for the analysis and segmentation of protein-protein interactions (PPI) images ( 38 ), Automatic segmentation of subfigure image panels for multimodal biomedical document retrieval ( 39 ), Ontology based information retrieval from medical Images using Low Level feature extraction method ( 40 , 41 ), Parsing multi-panel collaged figures method for document image understanding ( 42 ), mining images for the detection and analysis of gel diagrams ( 43 ), bioimaging for complex networks and pathways analysis ( 44 ), automatic categorization and spatial distribution analysis of biomedical images ( 45 , 46 ), analysing the embedded structural properties of biomedical figures ( 47 ), Yale Image Finder ( YIF ) ( 48 ), integrating image data into biomedical text ( 49 ) etc. We also found some commercial applications (e.g.…”