This article explores the emergence of women in the United States as a liberal voting group in the 1980s and the impact of this development on the power of liberalism, amid the Reagan revolution – an era often viewed as the apogee of conservatism. As the Republican party shifted in a more conservative direction in the 1980s, gender started to correlate with partisan preference/election outcomes in enough contests to give credence to the belief that women were becoming a decidedly liberal voting bloc. Contemporaneously, the equality-seeking movements of the 1960s and 1970s began institutionalizing their operations and exploiting these demographic shifts, becoming more entrenched than ever within the internal politics of the Democratic party. The National Organization for Women (NOW), the largest liberal women's group, proved to be particularly successful in this respect. Therefore, by presenting substantial archival evidence that liberal politicians and organizations remained a dynamic political force during the 1980s, this article details the growing organizational prowess of NOW and examines how liberals resisted the conservative challenge to fashion a political approach suited to the ‘Reagan Era’.