Fifty years of enuretic alarms.

Efficacy of alarm intervention in primary monosymptomatic nocturnal enuresis in children

“…18,19 The accepted treatment period for nocturnal enuresis was reported by Forsythe to be 12-16 weeks. 20 In the present study it was found that reduction in mean number of wet night started from 8 weeks of intervention and best results were seen after 20 weeks. However in some studies alarm intervention was given for a longer duration.…”

Is Second-Line Enuretic Alarm Therapy after Unsuccessful Pharmacotherapy Superior to First-Line Therapy in the Treatment of Monosymptomatic Nocturnal Enuresis?

“…Even during the early period of using enuretic alarm devices, children wake up and learn to go to the toilet, being conditioned [12,13] . Although alarm devices have been accepted as the first choice in most of the Western countries, desmopressin is widely used because of its easy administration, rapid effect, and also because less motivation and cooperation are necessary [11,17,18] .…”

Treatment of childhood nocturnal enuresis: an examination of clinically relevant principles

“…However, the most problematic methodological issue was the treatment duration. Children were only treated for 2 weeks before crossover, which is suf®cient time to assess the effect of desmopressin but clearly insuf®cient to test the effectiveness of the alarm, as 5±12 weeks has been suggested as the mean treatment duration with an enuresis alarm [11,12]. Thus treatment success in the A+D group was arguably caused by a response to desmopressin, whereas insuf®cient duration of treatment in the A+P group must have contributed to the failure rate in this group.…”