Field Precision of Formaldehyde Sampling and Analysis Using NIOSH Method 3500

Akbar-Khanzadeh, Farhang; Park, Chong K.

doi:10.1202/0002-8894(1997)058<0657:fpofsa>2.0.co;2

Cited by 2 publications

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“…Further- (15) and this was measured and monitored four times an hour, by a photo ionization detector (Photocheck + 5000, Ionscience Co., UK). Precision of the measurement was controlled according to the 3500 method recommended by the National Institute of Occupational Health and Safety (NIOSH) (15,16). Selection of the materials and dimensions of the chamber, to make a reverberant chamber with defined dimensional proportions, were based on Bolt's chart, and the mice were exposed to a spectrally homogeneous sound field (100 ± 2 dB) at each point inside the reverberant chamber with a mini speaker (Visaton K50-RC) (17,18).…”

Section: Introductionmentioning

confidence: 99%

Effects of Simultaneous Exposure to Formaldehyde Vapor and Noise on Mouse Testicular Tissue and Sperm Parameters

et al. 2012

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This article has focused on investigating the effects of simultaneous formaldehyde and noise exposure on reproductive parameters in male mice. Background: Workers are often simultaneously exposed to formaldehyde and noise in workplaces, and noise can reinforce the harmful effects of some chemical pollutants. Objectives: This study aimed to investigate the effects of simultaneous formaldehyde and noise exposure on reproductive parameters in male mice. Materials and Methods: Forty eight National Medical Research Institute adult male mice were randomly assigned to control and experimental groups which were exposed to formaldehyde (10 ppm) (F), noise (100 dB) (N), and simultaneous formaldehyde with noise (NF), respectively for 10 days (8 hours a day). Animals were killed 24 hours following exposure (short-term effects) and the remainder was killed 35 days after the end of exposure (long-term effects). Sperm was analyzed by a computer aided sperm analysis system and histological changes in the testis were determined. Plasma concentrations of testosterone, LH, FSH were measured. Results: The results of the short-term analysis showed that serum testosterone in all exposure groups decreased significantly compared to the controls (P < 0.001). In the longterm analysis, the percentages of progressive motile sperm groups N, F, and NF were 33.73 ± 3.4, 26.65 ± 1.61, and 14.78 ± 4.65, respectively, which indicated a significant decrease (P < 0 .05) compared to the control group (44.47 ± 2.88). The progressive motile sperm in the simultaneous exposure group was less than the N and F groups (P < 0.001). Histological study of testes specimens in the experimental groups (F and NF) revealed displacement of germinal cells and degeneration of Leydig cells and seminiferous tubules. Conclusion: Exposure to formaldehyde vapor can destroy testicular structure and decrease percentages of sperm count and progressive motility. The present study indicated that a reduction in the percentage of progressive motile sperm may be potentiated by noise (700-5700 HZ) in the simultaneous exposure to formaldehyde and noise group. Thus, it can be anticipated that simultaneous exposure to formaldehyde and noise in workplaces can increase the possibility of damage to testicular structures and reproductive functions in humans, if the same effects transpire.

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Section: Introductionmentioning

confidence: 99%

Effects of Simultaneous Exposure to Formaldehyde Vapor and Noise on Mouse Testicular Tissue and Sperm Parameters

et al. 2012

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“…The large number of articles yielded by our search strategy was limited by the inclusion criteria to a total of 32 articles. The included articles (30 and two articles from electronic searches and the gray literature, respectively) are Hemminki et al, ; Heck et al, ; Swenberg et al, ; Kligerman et al, ; Hemminki et al, ; Lam et al, ; Morgan et al, ; Sauder et al, ; Casanova and Heck, ; Kulle et al, ; Sauder et al, ; Casanova et al, 1988, ; Akbar‐Khanzadeh and Park, ; McMartin et al, ; Keil et al, ; Thrasher and Kilburn, ; Bendino, ; Maroziene and Grazuleviciene, ; UNEP Chemicals, ; Liteplo and Meek, ; Ryan et al, ; Goyer et al, ; Zhu et al, ; Goyer, ; Duong et al, ; Hisamitsu et al, ; Klein et al, ; Rahimifard et al, ; US CDC, 2013.…”

Section: Resultsmentioning

confidence: 99%

Formaldehyde exposure and its effects during pregnancy: Recommendations for laboratory attendance based on available data

et al. 2015

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Formalin is commonly used in fixation of cadaveric specimens. Exposure to formaldehyde, a component of formalin and a known carcinogen, during gross anatomy laboratory dissection is a continuing concern for pregnant students and instructors. Since there is little literature on this specific topic, the current review was compiled in the hope of offering recommendations to pregnant students and instructors who are engaged in human anatomical dissection where formalin is used. Relevant articles were obtained through searches of PubMed and Google Scholar for the terms "formaldehyde," "pregnant," "formalin," and "exposure." A literature search was conducted for chemical information and articles about exposure as issued by government regulatory agencies and chemical companies that produce formaldehyde. This led to the compilation of 29 articles each of which included references to previous, relevant, human research. The reviewed literature contains data strongly suggesting that pregnancy can be affected by formaldehyde exposure. Therefore, on the basis our analysis, female students who might be pregnant should avoid formaldehyde exposure, including that in a gross anatomy laboratory. Instructors should find other means of ensuring anatomical competence for these students.

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Field Precision of Formaldehyde Sampling and Analysis Using NIOSH Method 3500

Cited by 2 publications

References 0 publications

Effects of Simultaneous Exposure to Formaldehyde Vapor and Noise on Mouse Testicular Tissue and Sperm Parameters

Effects of Simultaneous Exposure to Formaldehyde Vapor and Noise on Mouse Testicular Tissue and Sperm Parameters

Formaldehyde exposure and its effects during pregnancy: Recommendations for laboratory attendance based on available data

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