“…In recent decades, the main scientific directions in "ISFETology," the term proposed by P. Bergveld in 2003, were oriented on an advancement from the classical structure (conventional semiconductor-oxide-electrolyte structure) of a transistor to floating gate, extended gate, double gate structures and top gated structures, which can be modified with different nanomaterials. Among them are typically grapheme, [53,54] carbon nanotubes (CNT), [55,56] nanowires or other novel sensing materials based on modified MoS 2 , [57,58] In 2 O 3 , [59] diamond, [60,61] GaN, [62] Metal-Organic Frameworks, [63,64] and so on. [65] The number of American, European, and Japanese companies producing pH-selective transistors and portable measuring devices based on them for sale has almost halved over the past 15 years, although several Chinese companies (Huaibei Huadian Automation Technology Co, Hangzhou Sinomeasure Automation Technology Co, Nengshi Analytical Sensor Co, Shenzhen Oway Technology Co, and others) have emerged providing very cheap devices.…”