Field-effect transistor antigen/antibody-TMDs sensors for the detection of COVID-19 samples

Abstract

We fabricated sensors by modifying the surface of MoS2 and WS2 with COVID-19 antibodies and investigated their characteristics, including stability, reusability, sensitivity, and selectivity. Thiols and disulfanes in antibodies strongly...

Localized Excitons in Zn-Porphyrin Covalently Functionalized MoS2 and WS2

“…Figure shows the preparation scheme of 0D–2D heterostructures composed of TMDs. Monolayer semiconducting WS 2 ( 1a ) and MoS 2 ( 1b ) were synthesized by the NaCl-assisted CVD method. − A lipoic acid derivative of tetraphenyl porphyrin was obtained following a previous study and coordinated with Zn 2+ yielding 2 as proved by 1 H NMR and mass spectroscopy (Figure S1). By employing the 1,2-dithiolane addition protocol for the functionalization of TMDs, we obtained ZnP-WS 2 ( 3a ) and ZnP-MoS 2 ( 3b ).…”

“…Chemical vapor deposition (CVD) growth was carried out using a home-built thermal CVD setup. − Before CVD growth, (210 nm) SiO 2 /Si substrates 6 × 2 cm 2 were washed in piranha solution for 15 min under sonication, followed by 1 min of sonication in ultrapure H 2 O and MeOH. After the sonication, substrates were dried using N 2 blowing and then were heated at 735 °C under an airflow of 400 mL/min for 30 min.…”

“…Indeed, such chemical reactions preserve or even improve the intrinsic properties of TMDs due to sulfur healing. − For example, dithiolanes bearing 0D chromophores, such as porphyrin, − phthalocyanine, quantum dots, or perylediimide, have been synthesized and employed to functionalize few-layered TMDs covalently. However, these examples only show functionalization at the edges, and the covalent functionalization of chromophores on the basal plane of TMDs has been exclusively explored for biosensors …”

Insulating 6,6‐Phenyl‐C61‐butyric Acid Methyl Ester on Transition‐Metal Dichalcogenides: Impact of the Hybrid Materials on the Optical and Electrical Properties

“…Briefly, [6,6]‐Phenyl C 61 butyric acid methyl ester (PCBM) was hydrolyzed according with the bibliography and further coupled with cysteine [34,35] . On the other hand, TMDs (MoS 2 , MoSe 2 , MoTe 2 , WS 2 , WSe 2 , WTe 2 , MoO 2 and WO 2 ) were synthesized by chemical vapor deposition (CVD), employing NaCl as a promotor [9,32,33,36] . All the conditions are shown at supporting information and table S1.…”

“…ZnP was completely insulated in regions of 1 nm 2 and a new interlayer exciton with a lifetime of 3.5 ns was detected. In addition, thiols owned in antibodies can covalently react with the basal plane of MoS 2 or WS 2 , enabling the development of reusable biosensors for COVID‐19 detection [33] . However, this new covalent functionalization strategy has only been employed with MoS 2 or WS 2 and its effects with other chalcogens such as Se or Te remains totally unexplored.…”