Fibrous topology promoted pBMP2-activated matrix on titanium implants boost osseointegration
Ting He,
Yichun Wang,
Ruohan Wang
et al.
Abstract:Titanium (Ti) implants have been extensively used after surgical operations. Its surface bioactivity is of importance to facilitate integration with surrounding bone tissue, and ultimately ensure stability and long-term functionality of the implant. The plasmid DNA-activated matrix (DAM) coating on the surface could benefit osseointegration but is still trapped by poor transfection for further application, especially on the bone marrow mesenchymal stem cells (BMSCs) in vivo practical conditions. Herein, we con… Show more
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