Fibrous hamartoma of infancy

Vinayak, Rohan S; Kumar, Sumit; Chandana, Sudhir; Trivedi, Priti

doi:10.4103/2229-5178.79867

Cited by 12 publications

(7 citation statements)

References 10 publications

(14 reference statements)

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“…33 The differential diagnosis for subcutaneous swelling in an infant includes both benign and malignant soft tissue tumours such as epidermoid cyst, recurring digital fibrous tumour, juvenile aponeurotic fibroma, juvenile hyaline fibromatosis, palmoplantar fibromatosis, histiocytoma, leiomyosarcoma, fibrosarcoma. 27,37 In our study we reported total 20 hamartoma cases, out of which patient with intestinal hamartoma died due to cardiopulmonary arrest. Laryngeal hamartoma patient presented with stridor which is near to fatal.…”

Section: Discussionmentioning

confidence: 83%

Study of hamartomatous lesions along with its fatality with review of literature

Sonwane,

Gonjari,

Anjum

et al. 2023

IJPO

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Albrecht introduced the concept of hamartoma at the beginning of twentieth century to designate a tumor like or non-neoplastic malformation or inborn error of tissue development. They arise virtually in all organs. They may derive from any three germinal layer of which mesodermal derived overgrowth is most common. They are slow growing and have self-limited growth. The formation of these growth take place by abnormal mixing of tissue in course of development. Present retrospective study was conducted in pathology department over a period of 2 years from July 2020 to June 2022. Total twenty cases were included in study and it was observed that twelve cases occurred in head and neck region, one case occurred over chest, one case in gastrointestinal tract and six cases in extremities. It is important to differentiate hamartomas from related lesions like choristoma, teratoma and benign tumors to avoid aggressive treatment.

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Section: Discussionmentioning

confidence: 83%

Study of hamartomatous lesions along with its fatality with review of literature

Sonwane,

Gonjari,

Anjum

et al. 2023

IJPO

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“…FHI is a soft tissue mass with a characteristic morphology including three histologic components: intersecting fascicles of dense fibrocollagenous tissue, loosely textured areas of immature basophilic or myxoid round or primitive mesenchymal cells, and mature adipose tissue ( 3 ). FHI is usually diagnosed before the age of 2 years and males are more commonly affected (2.4:1) ( 4 ). Most frequently, FHI presents as a solitary nontender soft tissue mass involving the axilla, upper arm, trunk, inguinal region, and chest wall.…”

Section: Discussionmentioning

confidence: 99%

CT and MRI Features of Middle Ear Fibrous Hamartoma of Infancy: A Case Report

Baek

Kim

Lim

2022

J Korean Soc Radiol

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Fibrous hamartoma of infancy in the middle ear is extremely rare. We report the case of a 26-month-old male patient who presented with a mass in the left middle ear. A temporal bone CT scan showed complete opacification of the left middle ear and mastoid air cells without ossicular erosion. On MRI, the mass revealed heterogeneous signal intensities indicative of fat and fibrous components. A definitive diagnosis was made postoperatively based on the histological results. Although rare, fibrous hamartoma of infancy should be considered as a differential diagnosis of a middle ear mass during childhood.

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“…FHI is most commonly found in axilla, shoulder, upper arm, inguinal region, and chest wall. Less common locations include head and neck, scrotum, legs, and foot [4].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Fibrous Hamartoma of Infancy: A Clinicopathological Diagnosis at a Tertiary Hospital, Eastern Nepal

Lama

Upadhyaya

Adhikari

et al. 2019

Case Reports in Pathology

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Background. Fibrous hamartoma of infancy is a rare soft tissue lesion of infants and young children with characteristic triphasic morphology. Case Description. An 18-month-old female child was presented with complaints of swelling over right leg shin since birth. On examination, a lump of size 7x3 cm was identified which was mobile and nontender. Local excision was performed and tissue sent for histopathological examination. On gross examination, a globular, capsulated, firm to hard tissue had cut section revealing solid grey-white to grey-brown lesion with myxoid areas identified. Microscopic examination revealed a poorly circumscribed lesion comprising intersecting trabeculae of fibrous tissue, areas of immature oval and stellate cell within myxoid matrix, and varying amounts of interspersed mature fat cells. Conclusion. Even though fibrous hamartoma of infancy is a rare benign entity with limited clinical knowledge, proper diagnosis is mandatory as its prognosis is excellent.

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Fibrous hamartoma of infancy

Cited by 12 publications

References 10 publications

Study of hamartomatous lesions along with its fatality with review of literature

Study of hamartomatous lesions along with its fatality with review of literature

CT and MRI Features of Middle Ear Fibrous Hamartoma of Infancy: A Case Report

A Rare Case of Fibrous Hamartoma of Infancy: A Clinicopathological Diagnosis at a Tertiary Hospital, Eastern Nepal

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