Fibromyalgia syndrome in chronic urticaria patients

Abstract

Background and Design:The aim of our study was to determine the frequency of fibromyalgia syndrome in chronic urticaria patients. Materials and Methods: The study was carried out with the participation of 100 chronic urticaria patients and 61 control group patients. Chronic urticaria patients were investigated for the etiology of urticaria and the autologous serum skin test was performed in those patients. Both the chronic urticaria patients and the controls were evaluated for fibromyalgia syndrome, and the patients fulfilling the diagnostic criteria were diagnosed to have fibromyalgia syndrome. Results: The frequency of fibromyalgia syndrome was significantly higher in chronic urticaria patients (23%), than in the control group (1.6%). All the patients, who were diagnosed with fibromyalgia syndrome, were female and the rate of female gender was significantly higher than in the group without fibromyalgia syndrome. Thyroid autoimmunity was positive in 26% of chronic urticaria patients. No significant difference was detected in the frequency of thyroid autoimmunity and autologous serum skin test positivity between the patients with and without fibromyalgia syndrome. Conclusion:The prevalence of fibromyalgia syndrome in chronic urticaria patients is higher than in the general population. Therefore, we suggest evaluation of chronic urticaria patients in terms of fibromyalgia syndrome which is a disease that decreases the quality of life considerably. Furthermore, in order to treat these two diseases effectively, future studies are necessary to determine the common points in the pathogenesis. (Turkderm 2014; 48: 215-8)

Relationship Between Chronic Spontaneous Urticaria and Fibromyalgia Syndrome

“…In the current study, the FMS incidence in CSU patients (26.4%) was significantly higher than in the control group (8.2%). Similar studies comparing FMS prevalence in patients with chronic urticaria and healthy volunteers have shown that the FMS incidence in the urticaria group varied between 9.7% and 70.6% (15)(16)(17)(18)(19)(20). In all these studies, a higher FMS prevalence was observed in the urticaria group than in the control group, and, similar to our study, the difference in FMS prevalence between these two groups was statistically significant (15)(16)(17)(18)(19).…”

“…Similar studies comparing FMS prevalence in patients with chronic urticaria and healthy volunteers have shown that the FMS incidence in the urticaria group varied between 9.7% and 70.6% (15)(16)(17)(18)(19)(20). In all these studies, a higher FMS prevalence was observed in the urticaria group than in the control group, and, similar to our study, the difference in FMS prevalence between these two groups was statistically significant (15)(16)(17)(18)(19). Torresani et al compared 126 patients with chronic urticaria with 50 controls and used ACR 1990 criteria for diagnosing FMS.…”

Fibromyalgia Syndrome and Vitiligo: A Novel Association

“…12 Some studies have investigated FMS incidence in dermatologic disorders such as psoriasis 13 and chronic urticaria. 14 The FMS syndrome is known to cause functional disability and have a negative impact on patient's quality of life (QoL). 15 Moreover, depression and/or anxiety are important parameters in criteria for diagnosis of FMS.…”