Fibromyalgia and the Risk of a Subsequent Motor Vehicle Crash

Redelmeier, Donald A.; Zung, Jeremy D.; Thiruchelvam, Deva; Tibshirani, Robert

doi:10.3899/jrheum.141315

Cited by 13 publications

(14 citation statements)

References 32 publications

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“…Each pregnancy was categorised as complicated or not complicated by a motor vehicle crash, defined as a traffic event sending the woman to an emergency department. 37 Regardless of crashes, we also distinguished each pregnancy followed by a preterm delivery (International Statistical Classification of Diseases (ICD) V.10 codes O60) or followed by an at-term or post-term delivery.…”

Section: Methodsmentioning

confidence: 99%

Motor vehicle crashes during pregnancy and cerebral palsy during infancy: a longitudinal cohort analysis

et al. 2016

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ObjectivesTo assess the incidence of cerebral palsy among children born to mothers who had their pregnancy complicated by a motor vehicle crash.DesignRetrospective longitudinal cohort analysis of children born from 1 April 2002 to 31 March 2012 in Ontario, Canada.ParticipantsCases defined as pregnancies complicated by a motor vehicle crash and controls as remaining pregnancies with no crash.Main outcomeSubsequent diagnosis of cerebral palsy by age 3 years.ResultsA total of 1 325 660 newborns were analysed, of whom 7933 were involved in a motor vehicle crash during pregnancy. A total of 2328 were subsequently diagnosed with cerebral palsy, equal to an absolute risk of 1.8 per 1000 newborns. For the entire cohort, motor vehicle crashes correlated with a 29% increased risk of subsequent cerebral palsy that was not statistically significant (95% CI −16 to +110, p=0.274). The increased risk was only significant for those with preterm birth who showed an 89% increased risk of subsequent cerebral palsy associated with a motor vehicle crash (95% CI +7 to +266, p=0.037). No significant increase was apparent for those with a term delivery (95% CI −62 to +79, p=0.510). A propensity score-matched analysis of preterm births (n=4384) yielded a 138% increased relative risk of cerebral palsy associated with a motor vehicle crash (95% CI +27 to +349, p=0.007), equal to an absolute increase of about 10.9 additional cases per 1000 newborns (18.2 vs 7.3, p=0.010).ConclusionsMotor vehicle crashes during pregnancy may be associated with an increased risk of cerebral palsy among the subgroup of cases with preterm birth. The increase highlights a specific role for traffic safety advice in prenatal care.

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Section: Methodsmentioning

confidence: 99%

Motor vehicle crashes during pregnancy and cerebral palsy during infancy: a longitudinal cohort analysis

et al. 2016

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“…Alcohol use disorder hospitalizations were identified by an ICD-9-CM or ICD-10-CM ( International Classification of Diseases, Ninth Revision or International Classification of Diseases, 10th Revision, Clinical Modification ) code in the primary position and excluding hospitalizations corresponding to drug counseling and rehabilitation/detoxification (see Supplementary Material 1, http://links.lww.com/RHU/A278 for details), a validated approach used previously 21–23 . Musculoskeletal diseases were identified by the presence of the following diagnostic codes in people with an index AUD hospitalization as previously 24–28 : gout: 274.xx or M10.xxx; RA: 714.xx or M06.xxx; fibromyalgia: 729.1 or M79.7; OA: 715.xx or M15.xxx - M19.xxx; or LBP: 724.2 or M54.5.…”

Section: Methodsmentioning

confidence: 99%

Epidemiology and Outcomes of Alcohol Use Hospitalizations in People With Gout, Rheumatoid Arthritis, Fibromyalgia, Osteoarthritis, or Low Back Pain

Singh

2021

J Clin Rheumatol

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To examine the incidence, time trends, and outcomes of alcohol use disorder (AUD) hospitalizations in people with gout, rheumatoid arthritis (RA), fibromyalgia, osteoarthritis, or low back pain (LBP).Methods: We used the US National Inpatient Sample data from 1998 to 2016. We examined the rates of AUD hospitalizations in musculoskeletal diseases (MSDs), based on the presence of diagnostic codes for AUD in the primary and MSDs in a secondary position. Multivariable-adjusted (age, sex, race, and income) health care utilization and in-hospital mortality were compared by the presence/absence of MSDs, using linear or logistic regression.Results: Alcohol use disorder hospitalizations increased over the 19-year study period from 1998 to 2014 to 3-fold higher in gout, osteoarthritis, or LBP; 3.5-fold in RA; and 4.5-fold in fibromyalgia. Compared with AUD hospitalizations in people without each respective MSD, adjusted total hospital charges were $3913 higher in people with gout and $1368 to $1614 lower for osteoarthritis, fibromyalgia, or LBP over the study period (all significant) and not significantly different for RA. The adjusted odds of hospital stay of more than 3 days were significantly higher for all 5 MSDs, with odds ratio ranging 1.10 for LBP to 1.34 for gout. The adjusted odds of in-hospital mortality were significantly lower for all 5 MSDs, with odds ratio ranging from 0.21 for fibromyalgia to 0.50 for gout. Conclusions:In a national US study, the rate of AUD hospitalizations increased in all 5 MSDs. Providers and patients with MSDs should be counseled regarding the risk and impact of alcohol use. Interventions to reduce AUD hospitalization-associated health care burden in MSD are needed.

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“…All Ontario residents are covered by a universal healthcare insurance, and all emergency department visits including RTI are captured in the computerized administrative datasets. These linkages have allowed addressing many health services research questions (Scales et al, 2006;Redelmeier et al, 2010;Redelmeier et al, 2014;Redelmeier et al, 2015;Lustig et al, 2016). We used these linked datasets to conduct a population-based longitudinal cohort analysis where the main predictor was self-reported risky gambling and the main outcome was a subsequent RTI as a driver, pedestrian, or bicyclist.…”

Section: Study Design and Settingmentioning

confidence: 99%

Gambling and Subsequent Road Traffic Injuries: A Longitudinal Cohort Analysis

Bhatti

Thiruchelvam

Redelmeier

2019

Journal of Addiction Medicine

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Background: To compare the risks of a road traffic injury (RTI) crash among adults who were involved in high-risk gambling and those who did not gamble. Methods: We conducted a linked longitudinal cohort analysis of adult persons in large population survey conducted during 2007 and 2008 in Ontario, Canada. We used responses to Problem Gambling Severity Index to distinguish persons as nongamblers, no-risk, lowrisk, or high-risk gamblers. All persons were subsequently monitored for a subsequent RTI crash as a driver, pedestrian, or bicyclist up to March 31, 2014, through health insurance databases. We estimated relative risks as rate ratios (RRs) with 95% confidence intervals (95% CIs).Results: In all, 30,652 adults were included, of whom 52% selfidentified as gamblers, including 49% as no-risk gamblers, 2% as low-risk gamblers, and 1% as high-risk gamblers. During a median follow-up period of 6.8 years, 708 participants (2%) were involved in 821 RTI crashes. The absolute risks of an RTI were 6.4 per 1000 person-years (95% CI 3.7-10.4) in high-risk gamblers and 3.6 per 1000 person-years (95% CI 3.2-4.0) in nongamblers. The relative risks for RTI crashes were significantly higher in high-risk gamblers than in nongamblers (adjusted RR 1.68, 95% CI 1.03-2.76). The risks for RTI crashes as a driver were augmented in high-risk gamblers than in nongamblers (RR 1.97, 95% CI 1.13-3.43). Conclusions: We found an increased risk of an RTI crash among drivers who self-identified as high-risk gamblers. Further research exploring the underlying mechanisms of these associations might interest health professionals to monitor RTI risks in adults involved in high-risk gambling.

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Fibromyalgia and the Risk of a Subsequent Motor Vehicle Crash

Abstract: A diagnosis of FM is associated with an increased risk of a subsequent motor vehicle crash that might justify medical interventions for traffic safety.

Cited by 13 publications

References 32 publications

Motor vehicle crashes during pregnancy and cerebral palsy during infancy: a longitudinal cohort analysis

Motor vehicle crashes during pregnancy and cerebral palsy during infancy: a longitudinal cohort analysis

Epidemiology and Outcomes of Alcohol Use Hospitalizations in People With Gout, Rheumatoid Arthritis, Fibromyalgia, Osteoarthritis, or Low Back Pain

Gambling and Subsequent Road Traffic Injuries: A Longitudinal Cohort Analysis

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