Fibromatosis (Desmoid Tumor) Involving the Orbit and Cheek

Amerasinghe, Nishani; Rogers, Simon; Rowlandson, P.; Köhler, Jan; Hodgkins, P R

doi:10.1016/j.jaapos.2006.04.008

Cited by 10 publications

(3 citation statements)

References 11 publications

(7 reference statements)

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“…For the pediatric population, the mandible is the most frequently affected site in the head and neck district [ 21 , 22 ]. Orbital location is unusual and rare for the desmoid fibromatosis, and only four cases had been described in literature [ 23 – 26 ]. Differential diagnosis in the pediatric population and in this anatomical location can be done with cranial/nodular fasciitis, low-grade fibromyxosarcoma, low-grade myofibroblastic sarcoma, lipofibromatosis, malignant peripheral nerve sheath tumor, myofibroma, leiomyosarcoma, inflammatory myofibroblastic tumor, and hypertrophic scar [ 13 , 27 ].…”

Section: Discussionmentioning

confidence: 99%

Orbital Desmoid-Type Fibromatosis: A Case Report and Literature Review

Moro

Angelis

Gasparini

et al. 2018

Case Reports in Oncological Medicine

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.Purpose. Desmoid-type fibromatosis is a benign fibrous neoplasia originating from connective tissue, fascial planes, and musculoaponeurotic structures of the muscles. Currently, there is no evidence-based treatment approach available for desmoid fibromatosis. In this article, a case of a patient in the pediatric age affected by desmoid fibromatosis localized in the orbit is presented. e aim of the article is to describe this unusual and rare location for the desmoid fibromatosis and outline the principle phases in the decision-making process and the therapeutic alternatives for a patient affected by desmoid fibromatosis. Methods. e protocol of this review included study objectives, search strategy, and selection criteria. e primary end point of this study was to analyze the head and neck desmoid fibromatosis. e secondary end point was to identify the available therapies and assess their specific indications. Results. e mean age of patients was 18.9 years ranging from 0 to 66, and 52% were female. A bimodal age distribution was observed, and two age peaks were identified: 0-14 years (57%) and 28-42 years (18%). e most common involved areas were the mandible (25%) followed by the neck (21%). In 86% of the cases, the treatment was the surgical resection of the disease, and only in 5% of the cases, the surgical resection was followed by adjuvant radiotherapy. Conclusion. e orbital location is extremely rare, especially in the pediatric population. e management of desmoid fibromatosis is based on the function preservation and the maintenance of a good quality of life, but in case of symptomatic patients or aggressive course of the disease or risk of functional damages, the surgical approach may be considered. erapeutic alternatives to surgical resection are radiotherapy and systemic therapy.

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Section: Discussionmentioning

confidence: 99%

Orbital Desmoid-Type Fibromatosis: A Case Report and Literature Review

Moro

Angelis

Gasparini

et al. 2018

Case Reports in Oncological Medicine

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“…Histologiquement, la tumeur est formée d'une proliféra-tion de cellules allongées fusiformes de petites tailles uniformes séparées par un tissu collagène (7,8,9). L'imagerie a surtout un intérêt dans le bilan d'extension alors que la clé du diagnostic positif est représentée par l'examen anatomopathologique (10). Le traitement est chirurgical.…”

Section: Discussionunclassified

Fibromatose desmoïde à localisation nasale

Kharrat¹,

Sahtout²,

Charrada³

et al. 2010

Journal Tunisien d'ORL Et De Chirurgie Cervico-Faciale

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“…To the authors’ knowledge, there are fewer than 10 case reports of pediatric DF with orbital involvement in the literature. 3–6 The majority of reported DF cases involving the orbit have been treated primarily with surgical excision. However, DF treated with surgery has been shown to be followed by high recurrence rates, despite partial or complete excision.…”

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confidence: 99%