Fibrolipomatosis of the transplanted kidney

Jv, Kaude; Tj, Fuller; Soong, John

doi:10.1055/s-0029-1231274

Cited by 5 publications

(6 citation statements)

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“…The first cases were published in 1976 by Kaude et al (6). To our knowledge, no case of fibrolipomatosis in a transplanted kidney has been reported since 1979 (6,7).…”

mentioning

confidence: 98%

“…The possible factors for fibrolipomatosis in our patients are unclear, but two of them had a history of UTI. Kaude et al (6,7) found that earlier rejection episodes may have been responsible for renal parenchyma atrophy and its replacement by fibrolipomatosis. They also suggested that high-dose steroid treatment may have contributed to the development of fibrolipomatosis.…”

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confidence: 99%

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Replacement Kidney Lipomatosis After Renal Transplantation

Laouad

Büchler²,

Weestel³

et al. 2005

Transplantation

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Renal sinus lipomatosis consists of abnormal fatty proliferation of the renal sinus, hilus, and perirenal spaces. Its pathogenesis is unknown, although it is generally associated with aging, renal atrophy, and long-standing chronic inflammation or urinary tract infection. Although this condition is rare, it may be important to recognize it in renal transplant recipients. We describe three cases of replacement kidney lipomatosis that occurred after cadaveric renal transplantation and discuss the possible differential diagnosis of this condition.

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“…The first cases were published in 1976 by Kaude et al (6). To our knowledge, no case of fibrolipomatosis in a transplanted kidney has been reported since 1979 (6,7).…”

mentioning

confidence: 98%

mentioning

confidence: 99%

Replacement Kidney Lipomatosis After Renal Transplantation

Laouad

Büchler²,

Weestel³

et al. 2005

Transplantation

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“…The discovery of RSL represents an uncommon finding of renal US either in normal subjects and in transplant recipients; indeed, there are just two papers describing RSL or RRL in these latter patients [ 4 , 5 ], despite the accurate and prolonged radiological followup of transplanted organs. At difference with previous reports, here we describe a peculiar case of RSL characterised by its huge dimension, the onset of acute renal dysfunction, and its “paradoxical” resolution.…”

Section: Discussionmentioning

confidence: 99%

“…RLS is a relatively rare condition in normal kidneys and is even less common in renal transplanted kidneys. The presence of RSL in a renal transplant recipient was described for the first time in 1979 [ 4 ], and, since then, only three additional cases have been mentioned in 2005 [ 5 ], although described as RRL. We report a peculiar clinical case of RSL, characterised by a huge dimension and by acute renal impairment, never described to date, with recovery of renal function after steroid treatment.…”

Section: Introductionmentioning

confidence: 99%

Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case

Apicella

Vallone

Vitale

et al. 2011

Case Reports in Transplantation

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Renal sinus lipomatosis (RSL) represents an abnormal proliferation of the adipose tissue surrounding the renal pelvis of uncertain origin, associated with aging, obesity, steroid excess, infections, and calculosis. It represents a rare complication in transplanted kidneys, and, despite the accurate and prolonged radiological followup of transplanted organs, only a few cases of RSL have been described in graft recipients, with no remarkable effects on renal function. The diagnosis relies on ultrasonography (US), magnetic resonance imaging (MRI), computed tomography (CT), and, finally, percutaneous biopsy. We describe the case of an extensive RSL in a 38-year-old renal transplant recipient, diagnosed by ultrasonography and computed tomography. The patient underwent a radiologic study because of an acute, asymptomatic renal impairment, that led to the diagnosis of a RSL of unusual dimensions, associated with a discrete hydronephrosis. Paradoxically, after a short course of steroids, the recovery of renal function and the partial resolution of calyceal dilatation were observed. The rarity of this affection, the need of a differential diagnosis with fat-containing tumors, and the possibility of parenchymal inflammation associated with RSL, potentially responsive to steroids, are also discussed.

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“…RSL is essentially described on native kidneys [ 1,2 ]. Possible risk factors for RSL include ageing, obesity and pathologic states that cause renal inflammation such as intense corticotherapy and/or early rejection for transplants.…”

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confidence: 99%