Fibrolipoma of buccal mucosa

Abstract

The lipoma is a very common benign tumor of adipose tissue, but its presence in the oral and oropharyngeal region is relatively uncommon. Fibrolipoma, a histological variant of lipoma, mostly affect the buccal mucosa and causes functional and cosmetic disabilities. Hence, accurate histopathological examination of lipomas is important for a correct treatment plan. This article describes a case of 10 year old girl with fibrolipoma of the buccal mucosa with a relevant review of tumors.

Fibrolipoma on upper eyelid in child

“…They occur mostly in adult men [ 4 ]. The age of the patient in this case was unusual, because these lesions peak incidence is in the fifth and sixth decade of life [ 1 ], [ 6 ], and they are rarely observed under the age of 20 years [ 6 ]. The clinical features of fibrolipoma vary according to their rate of growth, size and location.…”

“…Most of the lesions are less than 3 cm in size, but occasionally lesions become much larger. The consistency of this lesion varies from soft to firm, depending on quantity and distribution of fibrous tissue and depth of the tumor [ 1 ], [ 9 ]. A characteristic feature is a change in consistency and form of many of these tumors during contraction of involved muscle.…”

“…An association with genetic aberrations has been described for most types of adipocytic tumor and some trauma mechanisms, such as origin from lipoblastic embryonic cell nest, blunt trauma or chronic intermittent compression, have been associated with the apparition of lipomas [ 10 ]. Fatty degeneration, hormonal basis, infection and infarction, metaplasia of muscle cells and chronic irritation are probable representative theories to elucidate the pattern of lipoma [ 1 ], [ 2 ]. Fibrolipoma has been thought to be congenital to be caused by endocrinal imbalance, to be the product of a degenerated fibromatous tumor, or to arise from maturation of lipoblastomatosis [ 2 ].…”

“…Some of these show distinctive clinico-pathological features that are usually discernible only after histological examination [ 8 ]. Histologically, when there is a proliferation of components of mature adipose surrounded by dense fibrous cell connective tissue, the tumor is labeled a fibrolipoma [ 1 ], [ 3 ], [ 4 ]. Additionally, fibrolipomas have a higher proliferative activity than the classic variants [ 6 ], [ 9 ] but no differences in clinical behavior were noticed after surgical treatment [ 2 ].…”

“…Lipomas are common benign soft tissue neoplasms of mature adipose tissue [ 1 ], [ 2 ]. Although fat is abundant within the orbit, orbital lipomas are rare [ 3 ].…”