Abstract:Amaç. Gastrointestinal stromal tümörlerde (GİST) spesifik olarak ekspresyon gösteren ve kalsiyum bağımlı klorid kanalı olarak bilinen DOG1, gastrointestinal stromal tümörlerin diğer sarkomlardan ayrımında kullanılan tanısal bir belirteçtir. Çeşitli araştırmalarda Gastrointestinal stromal tümor dışı mezenşimal tümörlerde değişen oranda DOG1 ekspresyonu bildirilmiştir.
AbstractAim. DOG1 is a calcium-dependent chlorid channel, that shows specific expression in Gastrointestinal stromal tumors (GIST) can be used i… Show more
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