Fibroblast growth stimulation by extracts and compounds of Onosma argentatum roots

Phyto-Extracts in Wound Healing

“…In a couple of investigations, the principal active ingredients have been isolated to study especially their antimicrobial properties e.g. terpenes and terpenoids like gentiopicroside, sweroside and swertiamarine from Gentiana lutea; certain pentacyclic triterpenes (502-503) ; essential oil containing concentrates of eucalyptol (28) ; flavones such as kaempferol and quercetin and their derivatives (473); phenylpropanoid glycosides like verbascoside and teupolioside (504); cyanogenic glycosides such as sambunigrin as well as gallic acid and its derivatives (496).Wound healing substances isolated from Termalia arjuna were tannins (457); oleanoic acid from Anredra diffusa (70); polysaccharides from Opuntia ficus-indica (365); shikonin derivatives including deoxyshikonin, acetylshikonin, 3-hydroxyl isovaleryl shikonin and 5,8-O-dimethylacetylshikonin from Onosma argentatum (361); asiaticoside, asiatic acid and madecassic acid from Centella asiatica (146-147); quercetin , isorhammetin and kempferol from Hippophae rhamnoides (261) ; and curcumin from Curcuma longa (168). The list of well-charaterized newer active ingredients is increasing with a galloping speed.…”

Ethnopharmacological approaches to wound healing—Exploring medicinal plants of India

“…Some of the most important ones include tannins from Terminalia arjuna (Chaudhari and Mengi, 2006), oleanolic acid from Anredra diffusa (Letts et al, 2006), polysaccharides from Opuntia ficus-indica (Trombetta et al, 2006), gentiopicroside, sweroside and swertiamarine from Gentiana lutea (Ozturk et al, 2006), shikonin derivatives (deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin and 5,8-Odimethyl acetyl shikonin) from Onosma argentatum (Ozgen et al, 2006), asiaticoside, asiatic acid, and madecassic acid from Centalla asiatica (Maquart et al, 1999;Shukla et al, 1999a,b;Hong et al, 2005), quercetin, isorhamnetin and kaempferol from Hippophae rhamnoides (Fu et al, 2005), curcumin from Curcuma longa (Jagetia and Rajanikant, 2004), oleo-resin from Copaifera langsdorffi (Paiva et al, 2002), proanthocyanidins and reseveratrol from grapes (Brakenhielm et al, 2001;Khanna et al, 2002), acylated iridoid glycosides from Scrophularia nodosa (Stevenson et al, 2002), phenolic acids (protocatechuic, p-hydroxybenzoic, p-coumaric, ferulic and vanillic acids) from Chromolaena odorata (Phan et al, 2001), glycoprotein fraction from Aloe vera (Choi et al, 2001), (+)-epi-alpha-bisabolol from Peperomia galioides (Villegas et al, 2001), fukinolic acid and cimicifugic acids from Cimicifuga sps. (Kusano et al, 2001) and xyloglucan from Tamarindus indicus (Burgalassi et al, 2000).…”

Evaluation of wound healing properties of Arrabidaea chica Verlot extract

“…The therapeutic benefits of secondary metabolites of plant origin have been focused in many studies (MacKay and Miller, 2003;Houghton et al, 2005;Ozgen et al, 2006). Arrabidaea chica Verlot.…”