Fibroadenoma in a transgender woman

Abstract

A breast fibroadenoma is a common benign condition that is typically seen in younger women. Rarely has it been described in men and often because of prescribed medications, but for transgender women, this occurrence is even rarer. Endocrine therapy plays a key role in the transition of a transwoman from male to female of which oestrogen is the most common form. The use of cross-sex hormones such as oestrogen is becoming increasingly more utilized in this transition helping in feminization but also secondary breast development. However, this does result in the development of other breast pathologies that were almost never seen in their cis-male counterparts. Herein, we present the case of a 27-year-old transwoman who presented with a palpable breast lump after being on oral oestrogen therapy for 6 years. She proceeded to an excisional biopsy, which confirmed the lesion to be a benign fibroadenoma.

Benign phyllodes tumour in a transgender woman receiving hormonal therapy

“…More broadly, phyllodes tumours belong to a class of breast tumours called fibroepithelial lesions, which also include fibroadenomas 7. Although rare, fibroepithelial lesions have been reported in both cismen and transwomen 8–13. Here, we present a case of a transwoman, taking feminising hormone therapy, who is diagnosed with excisional biopsy-proven benign phyllodes tumour.…”