Fibrinolysin and the fluidity of the blood post mortem

Forensic implications of respiratory derived blood spatter distributions

“…Earlier, Virchow in 1871 [as quoted in Ref. [18]], had noted the very important point that capillary blood in the cadaver is always fluid and incoagulable. Lenggenhager in 1938 [as quoted in Ref.…”

The Fibrinolytic Activity of Blood Derived from Vessel Wall

“…In contrast to this no change in the fibrinogen level could be shown after activation of the endogenous fibrinolytic system following electroshock in rats [Fantl and Simon (10)]. K waan et al (21) observed that the adrenalin-induced plasmin showed similar charac teristics to the proteolytic enzyme of corpse blood described by Mole (25). A strup et al (2) believe that there are two different fibrinolytic pro-enzymes in human plasma, of which one is endo genous and the other can be activated by streptokinase.…”

“…Mole (25) was the first to propose that the increased fibrinolytic activity in these cases was released from the endothelium of these veins.…”

The Thrombogenic Hypothesis in Coronary Atherosclerosis

“…Soon after Dur/uid's theories were published it was suggested that the fibrinous incrustations on artery walls might be due to failure of fibrinolytic activity (27). Astrup has carried the sugges tion further, and suggested that small amounts of fibrin are con stantly being deposited on the vascular intima because of the ubiquity of thromboblastic agents and the latent activity of the coagulation process.…”