Fibrin glue as a protective tool for microanastomoses in limb reconstructive surgery

Langer, Stefan; Schildhauer, Thomas A.; Dudda, Marcel; Sauber, Jeannine; Spindler, Nick

doi:10.3205/iprs000073

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…Apart from preserving anastomotic patency, maintenance of pedicle position is another major concern. Spraying fibrin glue has been suggested for stabilizing the pedicle and preventing torsion [ 21 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Managing Vascular Pedicle Exposure in Free Tissue Transfer Using a Reprocessed Micronized Dermal Substitute in Lower Extremity Reconstructions

Kim,

Lee,

Park

et al. 2024

Bioengineering

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Lower extremity reconstruction is challenging because of its intricate anatomy and dynamic biomechanics. Although microsurgical free tissue transfer offers pivotal solutions to limited local tissue availability, vascular pedicle exposure after free tissue transfer is common. We evaluated a novel method of managing pedicle exposure after free tissue transfer using a reprocessed micronized dermal substitute. Ten patients who underwent lower-extremity reconstruction using free tissue transfer and micronized dermal substitute between January and December 2023 were retrospectively reviewed. When native tissue could not be closed over the pedicle, reprocessed micronized artificial dermal matrix (rmADM) was cut and stacked to protect and stabilize it. Epithelialization was achieved by secondary skin grafting or healing by secondary intention. Flap dimensions, recipient artery and vein, ADM size, time required for granulation tissue maturation and complete epithelialization, and flap outcomes were analyzed. The mean age was 55.80 ± 20.70 years, and six patients (60%) were diabetic. The mean rmADM coverage area was 8.70 ± 8.41 cm2, and the average time required for complete epithelialization was 50.89 ± 14.21 days. Except for one total necrosis due to bypass graft failure, nine limbs were successfully salvaged. Application of rmADM offers numerous advantages, including vascular collapse prevention, moisture maintenance, granulation tissue growth promotion, and pedicle stabilization.

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Section: Discussionmentioning

confidence: 99%

Managing Vascular Pedicle Exposure in Free Tissue Transfer Using a Reprocessed Micronized Dermal Substitute in Lower Extremity Reconstructions

Kim,

Lee,

Park

et al. 2024

Bioengineering

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“…The daily use of human fibrin glue improves surgical outcomes in many fields of general surgery 20 , 22 , 23 , 24 and plastic surgery. 25 , 26 , 27 However, there are a few contrary reports 28 , 29 , 30 , 31 and very few that suggest that fibrin glue should be used with caution in humans. 32 , 33 , 34 …”

Section: Introductionmentioning

confidence: 99%

The use of Fibrin Sealants in Reducing Drain Output in Abdominoplasty: Is it Useful?

Pieretti,

Gubitosi,

Mazzarella

et al. 2024

JPRAS Open

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“…Importantly, this method achieves these goals without increasing the risk of complications related to the use of fibrin glue or impairing the inspection and revision of the anastomosis (Andree et al, 2008;Kim et al, 2017;Langer et al, 2015;Schwabegger et al, 2008).…”

mentioning

confidence: 99%

The use of fibrin glue to stabilize and secure the lymphovenous anastomosis

Martini,

Meroni,

Scaglioni

2024

Microsurgery

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Fibrin glue as a protective tool for microanastomoses in limb reconstructive surgery

Cited by 5 publications

References 18 publications

Managing Vascular Pedicle Exposure in Free Tissue Transfer Using a Reprocessed Micronized Dermal Substitute in Lower Extremity Reconstructions

Managing Vascular Pedicle Exposure in Free Tissue Transfer Using a Reprocessed Micronized Dermal Substitute in Lower Extremity Reconstructions

The use of Fibrin Sealants in Reducing Drain Output in Abdominoplasty: Is it Useful?

The use of fibrin glue to stabilize and secure the lymphovenous anastomosis

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