“…102,104 Moreover, the structure of the fibrin-based hydrogel can be straightforwardly regulated by changing the concentration of thrombin and fibrinogen in the hydrogel precursors. Based on these characteristics, fibrinbased hydrogels are widely applied in bone tissue engineering, 102 neural tissue injury, 105 wound healing, 106 superficial cancer therapies 24,107,108 and so on. Fibrin can stimulate wound healing immediately by modulating cell behaviour and transforming into a delivery hydrogel system through fine-tuning for the extended release of therapeutic agents, growth factors, cells and so on.…”