Fibrillary glomerulonephritis: defining the disease spectrum

Immunotactoid Glomerulopathy

“…Most importantly, it will allow us to develop lesion-specific information for this group of patients in the future (39 -42). Prednisone 4 1 0 3 Cytotoxics 2 0 0 2 Prednisone and cytotoxics 22 2 0 20 Plasmapheresis 3 0 0 3 Nonsteroidals 2 0 0 2 Total 33 9% 0 91% a Data from references (3,17,20,24,29, and 39 to 42). …”

A Case of Immunotactoid Glomerulopathy with Rapid Progression to End-Stage Renal Disease

“…In a study of 16 patients treated with prednisone and/or cytotoxic agents only, two patients experienced partial remission of proteinuria, with the remaining 14 patients having no response. The partial remission seen in these two patients was most likely related to a nonspecific reversal of the acute inflammatory process [9]. In the Bridoux study, 10 of 12 nephrotic IGN patients with an underlying lymphoproliferative disease and/or paraproteinemia showed complete or partial remission of nephrotic syndrome after chemotherapy was completed [3].…”

Glomerulopathy with fibrillary and tubular deposits

“…Более тонкие хаотиче-ски расположенные фибриллы (при более пристальном изучении тоже тубулярные структуры) были отнесены к фибриллярному гломерулонефриту/нефропатии (ФГН). Ряд исследователей настаивают на важных клинических различиях между ИТН и ФГН [2,6,[9][10][11].…”