Fiberoptic and conventional phototherapy effects on the skin of premature infants

Dani, Carlo; Martelli, Elena; Reali, Maria Francesca; Bertini, Giovanna; Panin, Giorgio; Rubaltelli, Firmino F.

doi:10.1067/mpd.2001.111329

Cited by 22 publications

(9 citation statements)

References 10 publications

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“…This new type of phototherapy emits most of their light within the 450-470-nm spectrum for optimal bilirubin degradation. Preterm neonates, especially during the first week of life, have an increased TEWL due to the skin thinness, and this TEWL is particularly important during fiberoptic phototherapy [8].…”

Section: Abbreviationsmentioning

confidence: 99%

Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy

et al. 2007

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The aim of our study was to evaluate whether high-intensity gallium nitride light-emitting diode (LED) phototherapy (LPT) influences transepidermal water loss (TEWL) and cerebral hemodynamics in preterm neonates in comparison with conventional phototherapy (CPT). Thirty-one preterm infants were randomized for conventional (n = 14) and for LED (n = 17) phototherapy. All infants were studied using a Tewameter TM 210 and cerebral Doppler ultrasound immediately before phototherapy (time 0), 30 min (time 1), 1-6 h (time 2), and 12-24 h (time 3) after the start of phototherapy, and 6-12 h after discontinuing phototherapy (time 4). The study shows that LPT does not induce significant changes in TEWL (time 0: 2.75 +/- 4.71 ml/m(2)/h; time 3: 14.45 +/- 3.68 ml/m(2)/h), in peak systolic, end diastolic and mean cerebral blood flow velocity (CBFV), and in the resistence index (RI). On the contrary, CPT is associated with a significant increase of TEWL (time 0: 13.22 +/- 5.61 ml/m(2)/h; time 3: 20.94 +/- 3.21 ml/m(2)/h), which disappeared at time 4, when phototherapy had stopped. The peak systolic and mean CBFV increased, respectively, from 0.11 +/- 0.03 m/s at time 0 to 0.16 +/- 0.07 m/s at time 3. We conclude that LPT, emitting light within the 450-470-nm spectrum for optimal bilirubin degradation, can be preferable to CPT for the therapy of hyperbilirubinemia in preterm infants.

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Section: Abbreviationsmentioning

confidence: 99%

Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy

et al. 2007

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“…It has been reported that UV therapy is useful for treating more than 40 types of skin diseases and disorders such as such as psoriasis , or vitiligo , which could be treated by UV‐B radiation, and lichen sclerosus , morphea scleroderma , cutaneous T‐cell lymphoma, lupus erythematosus , which could be treated by UV‐A radiation. In the treatment of hyperbilirubinemia , commonly known as infant jaundice. For others such as acne vulgaris, use of UV radiation for treatment of various skin diseases has been well known for long time.…”

Section: Introductionmentioning

confidence: 99%

UVB‐emitting Gd³⁺‐activated M₂O₂S (where M = La, Y) for phototherapy lamp phosphors

2015

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Gd(3+)-activated oxysulphide (M2O2S) may be used to study Photoluminescence (PL) properties with respect to phototherapy. Gd(3+)-activated phosphor materials are widely used for phototherapy lamps. The Gd(3+) ion gives characteristic Narrow-Band (NB) emissions, in particular in the ultraviolet (UV) light region, that are used to treat more than 50 types of skin diseases. In this paper, M2O2S oxysulphide doped with Gd(3+) was synthesized by the solid-state flux fusion method and its down conversion spectral properties were studied as a function of different Gd(3+) concentrations. The sample was characterized by X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), Fourier Transform Infrared Spectroscopy (FT-IR), and PL and the crystal structure was also studied. The lanthanum oxysulphide (La2O2S)-activated Gd(3+) ion showed a sharp emission peak at 314 nm when excited at 275 nm excitation, whereas the yttrium oxysulphide (Y2O2S)-activated Gd(3+) ion showed a sharp emission at 316 nm when excited by 272 nm. The effect of concentration of the Gd(3+) ion on the luminescence properties of M2O2S:Gd(3+) phosphor was also studied. These phosphor materials activated with the Gd(3+) ion may be suitable for phototherapy lamps, which are used to treat many types of skin diseases such as psoriasis, vitiligo, or scleroderma.

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“…6 Current phototherapy systems use conventional compact fluorescent lamps or light-emitting diodes (LEDs), of which LEDs generate significantly higher light irradiance levels. 7 Phototherapy is generally considered a safe and well-tolerated therapy in neonatal jaundice. 8 However, some reports have indicated that phototherapy may cause oxidative stress, lipid peroxidation, and DNA damage.…”

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Impacts of phototherapy on DNA damage and total oxidant/ antioxidant status in jaundiced newborns

Bulut

Duruyen

2019

Turk J Pediatr

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Jaundice is common in newborn babies, and pathologic hyperbilirubinemia is frequently treated with phototherapy. Although it is considered to be safe, the side effects of phototherapy in newborns are still a matter of debate. In this study, the impacts of two types of phototherapy, conventional fluorescence and intensive light-emitting diodes (LED), on DNA damage and total oxidant/ antioxidant status in jaundiced newborns were assessed. The study group included 40 newborns (gestation age ≥ 37 weeks) on days 2-8 after birth. Newborns were divided into two groups on the basis of need for phototherapy: 20 newborns were exposed to conventional phototherapy (Group I); and 20 infants were exposed to intensive phototherapy (Group II). Blood samples were taken from all infants at admission and after phototherapy to determine plasma 8-hydroxy-2-deoxy-guanosine (8-OH-dG; a marker of DNA damage), total oxidant status (TOS), and total antioxidant capacity (TAC). The oxidative stress index (OSI) was also calculated. Demographic information was recorded, and DNA damage, TOS, and TAC were compared. There were no differences in demographic information between the two groups. There were no significant differences in DNA damage, TOS, TAC, and OSI between Groups I and II before phototherapy (p > 0.05) and no significant differences in DNA damage, TOS, TAC, and OSI between the two groups after phototherapy (p > 0.05). However, the TAC decreased significantly in both groups after phototherapy (p < 0.01). These findings suggest that conventional and intensive phototherapies do not affect DNA damage and oxidative stress, supporting the safety of its use as the preferred treatment for jaundiced newborns.

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Fiberoptic and conventional phototherapy effects on the skin of premature infants

Cited by 22 publications

References 10 publications

Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy

Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy

UVB‐emitting Gd³⁺‐activated M₂O₂S (where M = La, Y) for phototherapy lamp phosphors

Impacts of phototherapy on DNA damage and total oxidant/ antioxidant status in jaundiced newborns

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Fiberoptic and conventional phototherapy effects on the skin of premature infants

Cited by 22 publications

References 10 publications

Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy

Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy

UVB‐emitting Gd3+‐activated M2O2S (where M = La, Y) for phototherapy lamp phosphors

Impacts of phototherapy on DNA damage and total oxidant/ antioxidant status in jaundiced newborns

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UVB‐emitting Gd³⁺‐activated M₂O₂S (where M = La, Y) for phototherapy lamp phosphors