Fiber Segment-Based Degradation Methods for a Finite Element-Informed Structural Brain Network

Abstract

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Development and Implementation of a Transversely Isotropic Hyperelastic Constitutive Model With Two Fiber Families to Represent Anisotropic Soft Biological Tissues

“…This section briefly outlines a potential application of our constitutive model to brain tissue. Previously, a transversely isotropic hyperelastic constitutive model with a single fiber family was developed by Kraft and Dagro (27) and later used by McKee et al (28). In this model, diffusion spectrum imaging (DSI) was used to provide the constitutive model with the corresponding fiber directions.…”

“…The authors' solution was to provide an average over fiber directions as a first approximation with the intent to extend their model in the future to handle additional fiber families. Using some raw voxel data provided by these authors (27,28), we developed a simple method to extract two fiber directions. Figure 9 presents some example results of this procedure.…”