Fiber Bragg Grating Sensors-Based Assessment of Laser Ablation on Pancreas at 808 and 1064 nm Using a Diffusing Applicator: Experimental and Numerical Study

Namakshenas, Pouya; Bianchi, L.; Saccomandi, Paola

doi:10.1109/jsen.2023.3292987

Cited by 7 publications

(6 citation statements)

References 41 publications

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“…The FBG sensors allow for an independent measurement, wherein both the absolute temperature reached as well as the temperature distribution within the ablation zone could be monitored. 40 Further details on FBG-based thermometry are provided in the works of Korganbayev et al and Bianchi et al 41,42 We used a highly temperature-resistant polyimidecoated optical fiber inscribed with an array of 10 FBG sensors (FiSens GmbH, Braunschweig, Germany). Each sensor had a grating length of 1 mm and the spacing between consecutive gratings (edge-to-edge distance) was 1 mm.…”

Section: Temperature and Fiber Bragg Grating Sensorsmentioning

confidence: 99%

An anthropomorphic thyroid phantom for ultrasound‐guided radiofrequency ablation of nodules

Boers,

Brink,

Bianchi

et al. 2023

Medical Physics

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BackgroundNeedle‐based procedures, such as fine needle aspiration and thermal ablation, are often applied for thyroid nodule diagnosis and therapeutic purposes, respectively. With blood vessels and nerves nearby, these procedures can pose risks in damaging surrounding critical structures.PurposeThe development and validation of innovative strategies to manage these risks require a test object with well‐characterized physical properties. For this work, we focus on the application of ultrasound‐guided thermal radiofrequency ablation.MethodsWe have developed a single‐use anthropomorphic phantom mimicking the thyroid and surrounding anatomical and physiological structures that are relevant to ultrasound‐guided thermal ablation. The phantom was composed of a mixture of polyacrylamide, water, and egg white extract and was cast using molds in multiple steps. The thermal, acoustical, and electrical characteristics were experimentally validated. The ablation zones were analyzed via non‐destructive T2‐weighted magnetic resonance imaging scans utilizing the relaxometry changes of coagulated egg albumen, and the temperature distribution was monitored using an array of fiber Bragg grating sensors.ResultsThe physical properties of the phantom were verified both on ultrasound as well as in terms of the phantom response to thermal ablation. The final temperature achieved (92°C), the median percentage of the nodule ablated (82.1%), the median volume ablated outside the nodule (0.8 mL), and the median number of critical structures affected (0) were quantified.ConclusionAn anthropomorphic phantom that can provide a realistic model for development and training in ultrasound‐guided needle‐based thermal interventions for thyroid nodules has been presented.

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Section: Temperature and Fiber Bragg Grating Sensorsmentioning

confidence: 99%

An anthropomorphic thyroid phantom for ultrasound‐guided radiofrequency ablation of nodules

Boers,

Brink,

Bianchi

et al. 2023

Medical Physics

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“…Indeed, the miniaturized dimension, the immunity from electromagnetic interferences, and the possibility of performing quasi-distributed temperature measurements, thanks to multiple sensing points within a single ber and multiplexing capability, represent captivating features of FBGs. [40][41][42] Furthermore, the good metrological characteristics of the employed ber optic sensors, i.e., 2.0 mm spatial resolution and 0.1 °C accuracy, allow for the accurate detection of temperature gradients in the specimens.…”

Section: Photothermal Response Of Au Nr-loaded Hydrogel Samplesmentioning

confidence: 99%

On the role of polymeric hydrogels in the thermal response of gold nanorods under NIR laser irradiation

Lacroce,

Bianchi,

Polito

et al. 2023

Nanoscale Adv.

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“…Fiber Bragg grating sensors (FBGs) are very promising: they are micron-sized fiber-optic cables that allow temperature measurements over multiple points along the fiber [ 14 ]. By using multiple FBGs, one can achieve a tomographic reconstruction of the temperature distribution in the treated tissue and perform a feedback mechanism to confine the ablation zone [ 15 – 17 ]. Although temperature is a key parameter to directly assess the amount of energy absorbed by the tissues, a main limitation is the challenge of classifying the resulting thermal damage.…”

Section: Introductionmentioning

confidence: 99%

Optical signatures of thermal damage on ex-vivo brain, lung and heart tissues using time-domain diffuse optical spectroscopy

Bossi,

Bianchi,

Saccomandi

et al. 2024

Biomed. Opt. Express

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Thermal therapies treat tumors by means of heat, greatly reducing pain, post-operation complications, and cost as compared to traditional methods. Yet, effective tools to avoid under- or over-treatment are mostly needed, to guide surgeons in laparoscopic interventions. In this work, we investigated the temperature-dependent optical signatures of ex-vivo calf brain, lung, and heart tissues based on the reduced scattering and absorption coefficients in the near-infrared spectral range (657 to 1107 nm). These spectra were measured by time domain diffuse optics, applying a step-like spatially homogeneous thermal treatment at 43 °C, 60 °C, and 80 °C. We found three main increases in scattering spectra, possibly due to the denaturation of collagen, myosin, and the proteins' secondary structure. After 75 °C, we found the rise of two new peaks at 770 and 830 nm in the absorption spectra due to the formation of a new chromophore, possibly related to hemoglobin or myoglobin. This research marks a significant step forward in controlling thermal therapies with diffuse optical techniques by identifying several key markers of thermal damage. This could enhance the ability to monitor and adjust treatment in real-time, promising improved outcomes in tumor therapy.

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Fiber Bragg Grating Sensors-Based Assessment of Laser Ablation on Pancreas at 808 and 1064 nm Using a Diffusing Applicator: Experimental and Numerical Study

Cited by 7 publications

References 41 publications

An anthropomorphic thyroid phantom for ultrasound‐guided radiofrequency ablation of nodules

An anthropomorphic thyroid phantom for ultrasound‐guided radiofrequency ablation of nodules

On the role of polymeric hydrogels in the thermal response of gold nanorods under NIR laser irradiation

Optical signatures of thermal damage on ex-vivo brain, lung and heart tissues using time-domain diffuse optical spectroscopy

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