FGF21 improves ventricular remodeling in TAC induced heart failure rats
Liuzhang Fan,
MD;Jingjin Yan,
genshan Ma
et al.
Abstract:Background: Studies have found that elevated serum fibroblast growth factor 21 (FGF21) levels in patients with heart failure (HF) predicted poor prognosis. While preclinical studies have found that FGF21 plays a favorable role in the pathophysiological process of heart failure. Clinically, this increase in serum FGF21 seems to contradict the results of preclinical studies, therefore, the purpose of this study was to analyze whether FGF21 can improve ventricular remodeling in the HF rats, thereby improving card… Show more
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