Fever of Unknown Origin in the Elderly: Lymphoma Presenting as Vertebral Compression Fractures

Smith, Kimberly Y.; Bradley, Suzanne F.; Kauffman, Carol A.

doi:10.1111/j.1532-5415.1994.tb06080.x

Cited by 8 publications

(2 citation statements)

References 26 publications

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“…Past studies of fever of unknown origin (FUO) in the elderly have revealed that unlike for the young, a precise diagnosis can be made 87%-95% of the time [39][40][41]. In many cases, FUO is due to atypical presentations of common diseases [42]. Infection is the etiology in 25%-35% of cases, with tuberculosis occurring much more commonly in elderly than young patients with FUO.…”

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confidence: 99%

Fever in the Elderly

Norman

2000

Clinical Infectious Diseases

280

140

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Infections in the elderly, similar to other acute illnesses in this age group, may present in atypical, nonclassical fashions. Fever, the cardinal sign of infection, may be absent or blunted 20%-30% of the time. An absent or blunted fever response may in turn contribute to diagnostic delays in this population, which is already at risk for increased morbidity and mortality due to infection. On the other hand, the presence of a fever in the geriatric patient is more likely to be associated with a serious viral or bacterial infection than is fever in a younger patient. Finally, a diagnosis can be made in the majority of cases of fever of unknown origin (FUO) in the elderly. FUO is often associated with treatable conditions in this age group.

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confidence: 99%

Fever in the Elderly

Norman

2000

Clinical Infectious Diseases

280

140

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“…CT is better for evaluation of cortical destruction, although MR imaging and positron emission tomography/CT are more sensitive overall (59). Lymphoma may also manifest as fever of unknown origin and vertebral compression deformities in elderly patients (60).…”

Section: Lymphomamentioning

confidence: 99%