Fever of unknown origin in HIV‐infected patients: a critical analysis of a retrospective series of 57 cases

Abstract

Fever of unknown origin is a frequent occurrence in the course of HIV infection, and mycobacterial infection should be considered as a first-line diagnosis in such cases. The place of empiric antimycobacterial therapy in the diagnostic strategy requires further evaluation, but appears to be an alternative to multiple investigative procedures.

Diagnostic Value of Percutaneous Liver Biopsy in Fever of Unkown Origin in Patients with Human Immunodeficiency Virus Infection

“…Fever of unknown origin (FUO) has also been acknowledged as a major issue among these patients (2)(3)(4)(5). The advent of combined highly active antiretroviral therapy (HAART) has largely contributed to the declining morbidity and mortality rates among HIV-infected patients in both resource-rich and resource-constrained countries (6)(7)(8).…”

Detecting DisseminatedMycobacterium aviumComplex Infections in HIV-Positive Patients: The Usefulness of Bone Marrow Trephine Biopsy Specimens, Aspirate Cultures, and Blood Cultures

“…Frequently, patients with AIDS have unexplained fever 6 and undergo bone marrow biopsy as part of the workup to rule out the presence of malignancy or opportunistic infections. [7][8][9] Examination of the bone marrow aspirate and trephine biopsy specimens can reveal the presence of disseminated granulomatous disease, as well as microorganisms, including MAC, Mycobacterium tuberculosis, Cryptococcus neoformans, and Histoplasma capsulatum.…”

Fiebre de origen desconocido en pacientes VIH positivos

“…Existen dos factores sorprendentes en nuestra serie: en primer lugar la ausencia de casos de FOD relacionados con uso de fármacos, como han descrito otros autores (4,5,7). Esto podría explicarse porque en nuestro centro se retiraban sistemáticamente todos los fármacos en la primera fase del estudio de la FOD.…”