Fever of unknown origin in children: a systematic review

Chow, Annabelle; Robinson, Joan

doi:10.1007/s12519-011-0240-5

Cited by 121 publications

(112 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The reason for this variation would be the place of the study and variation in age of the patients (8). The prevalence of FUO related diseases is different according to the geographical region and age (4,(9)(10)(11)(12)(13)(14)(15). In the developing countries such as Iran, the most common cause of FUO is infectious disease and in conclusion, infectious respiratory along with TB are the most common infectious diseases for the children with FUO.…”

Section: Discussionmentioning

confidence: 99%

Fever of Unknown Origin in Children Aged Three Months to Fifteen Years

et al. 2015

View full text Add to dashboard Cite

Background: Fever of unknown origin (FUO) is defined as the presence of fever in a child for eight or more days that a careful history and physical examination and preliminary laboratory results failed to reveal the probable cause of the fever. The causes of FUO are different according to geographical regions and age. Objectives: The current study aimed to evaluate the common causes of childhood FUO in Zahedan, Iran. Patients and Methods:A six-year retrospective study was conducted on all admitted children aged from three months to fifteen years from January 2006 to January 2012 and those with the final diagnosis of FUO were selected for the study. Results: Finally, 1100 patients were found eligible for the study. The FUO causes were infectious diseases (55.1%), collagen vascular (4.6%), neoplasm (6.7%), miscellaneous (23.3%) and undiagnosed (10.3%). Conclusions: Most fever of unknown origin results from atypical presentation of common diseases like Tuberculosis, Salmonellosis, Brucellosis, and Pneumonia.

show abstract

Section: Discussionmentioning

confidence: 99%

Fever of Unknown Origin in Children Aged Three Months to Fifteen Years

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Establishing that the PFS is a diagnostic challenge for the medical team, it is necessary to carry out a systematic study, following a logical order that allows optimizing resources and avoiding diagnostic delays, to the benefit of the patient 3,4,10 .…”

Section: Introductionmentioning

confidence: 99%

Paniculitis como manifestación de síndrome febril prolongado en pediatría: Caso clínico

Silva

Radrigán

Lafuente

et al. 2017

Rev. chil. pediatr.

View full text Add to dashboard Cite

Introduction: Fever of unknown origin (FUO) is defined as fever over 7 to 10 days without a diagnosis despite a complete initial study. The most frequent causes are infections, autoimmune and tumors. Even though most cases are self-limited there is a minority that has an underlying etiology with an ominous forecast, encouraging a systematized study. Objective: To report a rare case of a boy who presented fever of unknown origin associated to panniculitis and was diagnosed of subcutaneous panniculitis-like-T cell lymphoma and to emphasis the importance of a sequential study of FUO, in order to reach a diagnosis in patients who need a timely intervention. Clinical case: A ten year old boy, previously healthy, presented subcutaneous nodular lesions of 2 month of evolution, located in abdominal region and extremities, given few symptoms, associated with prolonged fever. He was hospitalized for proper study, in first instance infectious and immune causes were discarded and through lesions biopsy the diagnose of subcutaneous panniculitis-like-T cell lymphoma was reached. Conclusion: When FUO is diagnosed, most prevalent causes must be discarded. Then, differential diagnosis, such as immune and neoplasic etiologies, have to be considered. If FUO is associated to elemental nodular lesions, biopsy must be indicated early, in order to find potential malignant cases, avoiding therapeutic delay.

show abstract

“…2,3 Nedeni bilinmeyen ateş hem tanısı hem de takibi açısından çocuk hekimlerini zorlayan bir durumdur. Tetkik edilen çocukların etiyolojisinde enfeksiyonlardan maligniteye kadar çok geniş yelpazede hastalıklar saptanabilmektedir.…”

unclassified

“…Tetkik edilen çocukların etiyolojisinde enfeksiyonlardan maligniteye kadar çok geniş yelpazede hastalıklar saptanabilmektedir. [3][4][5][6] Bu hastalarda doğru tanıya giden en önemli yol, iyi bir öykü ve fizik muayenedir. Yapılacak laboratuvar ve gö-rüntüleme testleri, öykü ve fizik muayeneden elde edilecek veriler ve hastaların klinik seyirlerine göre planlanmalıdır.…”

unclassified

“…7 Yapılan çalışmalarda, NBA nedeni ile araştırılan çocukların %20-78'inde enfeksiyonlar sorumlu bulunmuştur. 3 Çalışmamızda da NBA nedeni ile yatırılan hastalarda gözlenen en sık etiyolojik faktör %42,42 ile enfeksiyonlardır. Nitekim, Türkiye'de yapılan çalışmalar ve uluslararası sistematik incelemelerde de ilk üç sırada enfeksiyonlar, kollajen doku hastalıkları ve malignite yer almaktadır.…”

unclassified

See 1 more Smart Citation