Fever-induced epileptic encephalopathy in children (FIRES)

Abstract

Fever infection-related epilepticy syndrome, FIRES — rare severe epileptic encephalopathy infection or fever-induced refractory epileptic status developing in a previously healthy child. The etiology of FIRES remains unknown; post-inflammatory and autoimmune mechanisms are assumed. Recovery is possible, but the majority of children develop significant cognitive failure and refractory epilepsy.